All cells in nature are covered with a dense and complex array of glycan chains. Specific
recognition and binding of glycans is a critical aspect of cellular interactions, both within and …

The surface of all living cells is decorated with carbohydrate molecules. Hundreds of
functional proteins bind to these glycosylated ligands; such binding events subsequently …

Glycans are among the most intriguing carriers of biological information in living systems.
The structures of glycans not only convey the cells' physiological state, but also regulate …

Protein–glycan interactions mediate diverse biological processes in cell communication and
innate immunity. They involve the binding of a protein on one cell surface to a glycosylated …

Defining how a glycan-binding protein (GBP) specifically selects its cognate glycan from
among the ensemble of glycans within the cellular glycome is an area of intense study …

The adhesion force and specificity in the first experimental evidence for cell–cell recognition
in the animal kingdom were assigned to marine sponge cell surface proteoglycans …

Proteins that bind carbohydrate structures can serve as tools to quantify or localize specific
glycans in biological specimens. Such proteins, including lectins and glycan-binding …

It has been amply constated that sugar ligand multivalency increases lectin-binding avidities
dramatically, thereby modulating the capacity of carbohydrates to participate in …

Screening of glycan arrays represents a powerful, high-throughput approach to defining
oligosaccharide ligands for glycan-binding receptors, commonly referred to as lectins …

Carbohydrate-carrying molecules in the nervous system have important roles during
development, regeneration and synaptic plasticity. Carbohydrates mediate interactions …