Traumatic brain injury (TBI) can lead to significant neuropsychiatric problems and
neurodegenerative pathologies, which develop and persist years after injury …

Traumatic brain injury (TBI) is associated with an increased risk of cognitive, psychiatric, and
neurodegenerative complications that may develop after injury. Increased microglial …

Traumatic brain injury (TBI) can lead to secondary neuropsychiatric problems that develop
and persist years after injury. Mounting evidence indicates that neuroinflammatory …

The neuroinflammatory response to traumatic brain injury (TBI) is critical to both
neurotoxicity and neuroprotection, and has been proposed as a potentially modifiable driver …

As the major cellular component of the innate immune system in the central nervous system
(CNS) and the first line of defense whenever injury or disease occurs, microglia play a …

Background Traumatic brain injury (TBI) is a leading cause of death and disability that lacks
neuroprotective therapies. Following a TBI, secondary injury response pathways are …

Traumatic brain injury (TBI) remains one of the leading causes of mortality and morbidity
worldwide, yet despite extensive efforts to develop neuroprotective therapies for this …

Chronic neuroinflammation with sustained microglial activation occurs following severe
traumatic brain injury (TBI) and is believed to contribute to subsequent neurodegeneration …

Recent clinical studies indicate that traumatic brain injury (TBI) produces chronic and
progressive neurodegenerative changes leading to late neurologic dysfunction, but little is …

Traumatic brain injury (TBI) results in white matter injury (WMI) that is associated with
neurological deficits. Neuroinflammation originating from microglial activation may …