The use of vaccination against the influenza virus remains the most effective method of
mitigating the significant morbidity and mortality caused by this virus. Antibodies elicited by …

Pseudotype neutralization assays are powerful tools to study functional antibody responses
against viruses in low biosafety laboratories. However, protocols described in the literature …

The search for a test that can predict vaccine efficacy is an important part of any vaccine
development program. Although regulators hesitate to acknowledge any test as a true …

We developed an influenza hemagglutinin (HA) pseudotype library encompassing Influenza
A subtypes HA1-18 and Influenza B subtypes (both lineages) to be employed in influenza …

High-performance neutralizing antibody against influenza virus typically recognizes the
globular head region of its hemagglutinin (HA) envelope glycoprotein. To-date, approved …

Pseudotype reporter viruses provide a safe, quantitative, and high-throughput tool for
assessing antibody neutralization for many viruses, including high pathogenicity H5 and H7 …

Influenza is an infectious respiratory disease with significant morbidity and mortality rates
among people of all ages. Influenza viruses spread and evolve rapidly in the human …

Pseudotype reporter viruses are being used as safe, quantitative, and high-throughput tools
for assessing antibody neutralization for many viruses, including influenza. However …

Current influenza virus vaccines rely upon the accurate prediction of circulating virus strains
months in advance of the actual influenza season in order to allow time for vaccine …

Neutralizing antibody is associated with the prevention and clearance of influenza virus
infection. Microneutralization (MN) and hemagglutination inhibition (HI) assays are currently …