Innate lymphoid cells (ILC) in SARS-CoV-2 infection

A Kumar, W Cao, K Endrias, SV Kuchipudi… - Molecular Aspects of …, 2021 - Elsevier
Abstract Innate Lymphoid Cells (ILCs) are a class of innate immune cells that form the first
line of defense against internal or external abiotic and biotic challenges in the mammalian …

Adaptive immune cells are necessary for SARS-CoV-2–induced pathology

B Imbiakha, JM Sahler, DW Buchholz, S Ezzatpour… - Science …, 2024 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is causing the ongoing
global pandemic associated with morbidity and mortality in humans. Although disease …

Innate lymphoid cell composition associates with COVID‐19 disease severity

M García, E Kokkinou… - Clinical & …, 2020 - Wiley Online Library
Objectives The role of innate lymphoid cells (ILCs) in coronavirus disease 2019 (COVID‐
19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is …

[PDF][PDF] Innate immunity in COVID-19: Drivers of pathogenesis and potential therapeutic targets

V Ruenjaiman, N Hirankarn… - Asian Pacific journal of …, 2021 - apjai-journal.org
A novel severe acute respiratory syndrome COVID-19 caused by coronavirus SARS-CoV-2
has been confirmed to infect more than 100 million people globally, with mortality reaching …

Macrophages and dendritic cells are not the major source of pro-inflammatory cytokines upon SARS-CoV-2 infection

MA Niles, P Gogesch, S Kronhart… - Frontiers in …, 2021 - frontiersin.org
The exact role of innate immune cells upon infection with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and their contribution to the formation of the corona virus …

[HTML][HTML] Exhaustion and over-activation of immune cells in COVID-19: Challenges and therapeutic opportunities

M Alahdal, E Elkord - Clinical Immunology, 2022 - Elsevier
Exhaustion of immune cells in COVID-19 remains a serious concern for infection
management and therapeutic interventions. As reported, immune cells such as T effector …

Role of innate immunity in SARS-CoV-2 infection

Z Wang, F Cheng, Y Xu, X Li, S Meng - Biosafety and Health, 2023 - mednexus.org
During severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection, activated
macrophages, dendritic cells (DC), neutrophils, and natural killer (NK) cells are the first …

Antigen-Specific T Cells and SARS-CoV-2 Infection: Current Approaches and Future Possibilities

Z Nova, T Zemanek, N Botek - International Journal of Molecular Sciences, 2022 - mdpi.com
COVID-19, a significant global health threat, appears to be an immune-related disease.
Failure of effective immune responses in initial stages of infection may contribute to …

T cell responses to SARS-CoV-2 in humans and animals

SS Mattoo, J Myoung - Journal of Microbiology, 2022 - Springer
Abstract SARS-CoV-2, the causative agent of COVID-19, first emerged in 2019. Antibody
responses against SARS-CoV-2 have been given a lot of attention. However, the …

T cells: warriors of SARS-CoV-2 infection

P de Candia, F Prattichizzo, S Garavelli… - Trends in …, 2021 - cell.com
Severe infection with severe acute respiratory syndrome coronavirus (SARS-CoV)-2 is
characterized by massive cytokine release and T cell loss. The exaggerated host immune …