We sought to determine whether early nerve damage may be detected by corneal confocal
microscopy (CCM), skin biopsy, and neurophysiological tests in 86 recently diagnosed type …

Objectives Corneal confocal microscopy (CCM) is a rapid, non-invasive, reproducible
technique that quantifies small nerve fibres. We have compared the diagnostic capability of …

OBJECTIVE Impaired glucose tolerance (IGT) through to type 2 diabetes is thought to confer
a continuum of risk for neuropathy. Identification of subjects at high risk of developing type 2 …

Surrogate markers of diabetic neuropathy are being actively sought to facilitate the
diagnosis, measure the progression, and assess the benefits of therapeutic intervention in …

OBJECTIVE To assess the diagnostic utility of corneal confocal microscopy (CCM) for
diabetic peripheral neuropathy (DPN) and the risk factors for corneal nerve loss …

OBJECTIVE In vivo corneal confocal microscopy (IVCCM) has been proposed as a
noninvasive technique to assess small nerve fiber structural morphology. We investigated …

OBJECTIVE To establish if corneal nerve loss, detected using in vivo corneal confocal
microscopy (IVCCM), is symmetrical between right and left eyes and relates to the severity of …

OBJECTIVE Quantitative assessment of small fiber damage is key to the early diagnosis and
assessment of progression or regression of diabetic sensorimotor polyneuropathy (DSPN) …

Objective Corneal innervation is increasingly used as a surrogate marker of human diabetic
peripheral neuropathy (DPN) however its temporal relationship with the other microvascular …

Aims/hypothesis The accurate detection, characterization and quantification of human
diabetic neuropathy are important to define at risk patients, anticipate deterioration, and …