ACE inhibitors in heart failure: prospects and limitations

B Pitt - Cardiovascular drugs and therapy, 1997 - Springer
ACE inhibitors have been shown to be effective in reducing the morbidity and mortality of
patients with left ventricular systolic dysfunction, but their application to clinical practice in …

ACE inhibitors for the prevention and treatment of heart failure: why are they'under-used'?

JG Cleland - Journal of human hypertension, 1995 - europepmc.org
Currently there is concern that ACE inhibitors are not being utilised to their maximum
potential for the prevention or treatment of heart failure. Underutilisation of ACE inhibitors …

ACE inhibitors in heart failure: an update

WHT Smith, SG Ball - Basic Research in Cardiology, 2000 - Springer
Angiotensin-converting enzyme (ACE) inhibitors are now accepted as part of the routine
management of patients with heart failure. Their use has been mandated in all the new …

Current controversies with ACE inhibitor treatment in heart failure

FC Visser, CA Visser - Cardiology-Basel, 1996 - karger.com
Although the beneficial effects of angiotensin-con verting enzyme (ACE) inhibitors on symp
toms. morbidity and mortality have been proven beyond any doubt, some controversies …

Importance of angiotensin-converting enzyme inhibitors in myocardial infarction and congestive heart failure: implications for clinical practice

B Pitt - Cardiology, 1995 - karger.com
Angiotensin-converting enzyme inhibitors (ACE inhibitors) have been shown to be effective
in improving symptoms and survival in patients with systolic left ventricular dysfunction …

ACE inhibitors in non-ischaemic heart failure: results from the MEGA trials

JN Cohn - European heart journal, 1995 - academic.oup.com
Large-scale trials have demonstrated a consistent mortality reduction from angiotensin
converting enzyme (ACE) inhibitor therapy for chronic heart failure. Nonetheless, the …

Angiotensin II receptor antagonists in heart failure: rationale and design of the evaluation of losartan in the elderly (ELITE) trial

B Pitt, P Chang, PBMWWM Timmermans - Cardiovascular drugs and …, 1995 - Springer
Angiotensin-converting enzyme inhibitors (ACE-I) have been proven to be effective in
reducing morbidity and mortality in patients with heart failure or post-myocardial infarction …

Underutilization of ACE inhibitors in heart failure

AB Luzier, L DiTusa - Pharmacotherapy: The Journal of Human …, 1999 - Wiley Online Library
Although the beneficial effects of angiotensin‐converting enzyme (ACE) inhibitors in patients
with ventricular systolic dysfunction are well documented, historically, a large proportion of …

The clinical course of heart failure and its modificafion by ACE inhibitors: insights from recent clinical trials

JGF Cleland - European heart journal, 1994 - academic.oup.com
Our understanding of the clinical course of heart failure and the mechanism by which ACE
inhibitors reduce mortality and morbidity is being enhanced by recent results from large …

ACE inhibitors in heart failure: what more do we need to know?

C Demers, A Mody, KK Teo, RS McKelvie - American journal of …, 2005 - Springer
ACE inhibitors have significantly decreased cardiovascular mortality, myocardial infarction
(MI), and hospitalizations for heart failure (HF) in patients with asymptomatic or symptomatic …