Neoplastically transformed mouse and human keratinocytes elevate transactivation of both
activator protein 1 (AP‐1) and nuclear factor κB (NFκB) transcription factors. The present …

AP-1 transactivation appears to be required for mouse JB6 cell neoplastic transformation
induced by the tumor promoter TPA or epidermal growth factor (EGF). Exposure to AP-1 …

We previously reported that induced activator protein‐1 (AP‐1) transcriptional activity
appears to be required for tumor promoter–induced transformation in mouse epidermal JB6 …

Potential targets for chemoprevention of nonmelanoma skin cancer include UV‐induced
nuclear factor κB (NF‐κB) and activator protein‐1 (AP‐1) activation in keratinocytes …

Activation of activator protein 1 (AP-1) and nuclear factor κB (NFκB)–dependent transcription
is required for tumor promotion in cell culture models and transgenic mice. Dominant …

Cross-coupling of active protein-1 (AP-1) and nuclear factor (NF)-κB has been reported. In
the present study, we investigated the possibility that both of these two transcription factors …

Clonal variants of mouse epidermal JB6 cells that are genetically susceptible (P+) or
resistant (P−) to tumor promoter-induced neoplastic transformation exhibit differential …

The dominant negative c‐jun TAM‐67 has been shown to inhibit tumor promotion induced
by 12‐O‐tetradecanoylphorbol‐13‐acetate and okadaic acid (OA). To better understand this …

We reported previously that transcription factor nuclear factor (NF)-κB is constitutively
activated in human and murine squamous cell carcinomas (SCCs). The role of NF-κB in the …

Activator protein-1 (AP-1) is a transcription factor that consists of either a Jun-Jun
homodimer or a Jun-Fos heterodimer. Transactivation of AP-1 is required for tumor promoter …