Maternal genetic polymorphisms and unexplained recurrent miscarriage: a systematic review and meta‐analysis

X Shi, X Xie, Y Jia, S Li - Clinical Genetics, 2017 - Wiley Online Library
The roles of genetic polymorphisms in the pathogenesis of recurrent miscarriage (RM) have
been intensively studied. However, the results of these studies were inconsistent, especially …

Genetics of recurrent miscarriage: challenges, current knowledge, future directions

K Rull, L Nagirnaja, M Laan - Frontiers in genetics, 2012 - frontiersin.org
Recurrent miscarriage (RM) occurs in 1–3% of couples aiming at childbirth. Due to
multifactorial etiology the clinical diagnosis of RM varies. The design of genetic/“omics” …

Multifactorial etiology of recurrent miscarriage and its scientific and clinical implications

OB Christiansen, R Steffensen, HS Nielsen… - Gynecologic and …, 2008 - karger.com
A considerable proportion of recurrent miscarriage (RM) cases are caused by recurrent
chromosomally abnormal conceptions. However, in younger patients and patients with …

Family history and risk of miscarriage: A systematic review and meta‐analysis of observational studies

AMF Woolner, P Nagdeve, EA Raja… - Acta obstetricia et …, 2020 - Wiley Online Library
Introduction Miscarriage, a spontaneous pregnancy loss at< 24 weeks' gestation, is a
common complication of pregnancy but the etiologies of miscarriage and recurrent …

Genetics of recurrent miscarriage and fetal loss

MH Tur-Torres, C Garrido-Gimenez… - Best Practice & Research …, 2017 - Elsevier
Despite years of research, miscarriage, particularly when recurrent, continues to pose a
medical challenge. An embryo chromosomal error is responsible for 50–60% of recurrent …

Genetic variation within the hypothalamus-pituitary-ovarian axis in women with recurrent miscarriage

CW Hanna, KL Bretherick, CC Liu… - Human …, 2010 - academic.oup.com
Abstract BACKGROUND Recurrent miscarriage affects 1–2% of couples trying to conceive,
and is idiopathic in nearly half. Female fertility is controlled by the hypothalamus-pituitary …

Genetics of recurrent pregnancy loss among Iranian population

M Moghbeli - Molecular Genetics & Genomic Medicine, 2019 - Wiley Online Library
Background Recurrent pregnancy loss (RPL) is one of the most common reproductive
disorders which is defined as the occurrence of recurrent miscarriage before 24 weeks of …

The genetic architecture of sporadic and multiple consecutive miscarriage

T Laisk, ALG Soares, T Ferreira, JN Painter… - Nature …, 2020 - nature.com
Miscarriage is a common, complex trait affecting~ 15% of clinically confirmed pregnancies.
Here we present the results of large-scale genetic association analyses with 69,054 cases …

Structural genomic variation as risk factor for idiopathic recurrent miscarriage

L Nagirnaja, P Palta, L Kasak, K Rull… - Human …, 2014 - Wiley Online Library
Recurrent miscarriage (RM) is a multifactorial disorder with acknowledged genetic
heritability that affects∼ 3% of couples aiming at childbirth. As copy number variants (CNVs) …

Associations of recurrent miscarriages with chromosomal abnormalities, thrombophilia allelic polymorphisms and/or consanguinity in Saudi Arabia

RF Turki, M Assidi, HA Banni, HA Zahed, S Karim… - BMC medical …, 2016 - Springer
Background Recurrent pregnancy loss (RPL) or recurrent spontaneous abortion is an
obstetric complication that affects couples at reproductive age. Previous reports documented …