Recent advances in the generation, purification and cellular delivery of RNA have enabled
development of RNA-based therapeutics for a broad array of applications. RNA therapeutics …

Recent studies identified diverse RNAs including noncoding RNAs and their various action
mechanisms in the cells. These RNAs regulate a variety of cellular pathways and are …

RNA therapy refers to the treatment or prevention of diseases using RNA-based molecules.
The recent advent of a series of effective messenger RNA-based vaccines in response to the …

ABSTRACT RNA-based therapeutics are emerging as a powerful platform for the treatment
of multiple diseases. Currently, the two main categories of nucleic acid therapeutics …

Ribonucleic acid (RNA) therapeutics are being actively researched as a therapeutic
modality in preclinical and clinical studies. They have become one of the most ubiquitously …

Abstract Recently, United States Food and Drug Administration (FDA) and European
Commission (EC) approved Alnylam Pharmaceuticals' RNA interference (RNAi) therapeutic …

The growing knowledge on several classes of non-coding RNAs (ncRNAs) and their
different functional roles has aroused great interest in the scientific community. Beyond the …

Recent advances of biological drugs have broadened the scope of therapeutic targets for a
variety of human diseases. This holds true for dozens of RNA-based therapeutics currently …

RNA therapeutics refers to the use of oligonucleotides to target primarily ribonucleic acids
(RNA) for therapeutic efforts or in research studies to elucidate functions of genes …

Recently, there have been significant advances in the field of RNA‐based therapeutics
harnessing exogenous RNAs including small interfering RNA (siRNA), microRNA (miRNA) …