Oroxylin A: A promising flavonoid for prevention and treatment of chronic diseases

A Sajeev, M Hegde, S Girisa, TN Devanarayanan… - Biomolecules, 2022 - mdpi.com
There have been magnificent advancements in the understanding of molecular mechanisms
of chronic diseases over the past several years, but these diseases continue to be a …

Overview of oroxylin A: a promising flavonoid compound

L Lu, Q Guo, L Zhao - Phytotherapy Research, 2016 - Wiley Online Library
Oroxylin A is one of the main active components extracted from Scutellariae radix. It has
been proved that oroxylin A possesses a broad spectrum of pharmacological functions …

Modulation of diverse oncogenic signaling pathways by oroxylin A: An important strategy for both cancer prevention and treatment

A Sajeev, M Hegde, UD Daimary, A Kumar, S Girisa… - Phytomedicine, 2022 - Elsevier
Background Regardless of major advances in diagnosis, prevention and treatment
strategies, cancer is still a foreboding cause due to factors like chemoresistance …

Oroxylin a prevents inflammation‐related tumor through down‐regulation of inflammatory gene expression by inhibiting NF‐κB signaling

J Yao, R Hu, J Sun, B Lin, L Zhao, Y Sha… - Molecular …, 2014 - Wiley Online Library
Increasing evidence suggests that inflammatory microenvironment plays a critical role at
different stages of tumor development. However, the molecular mechanisms of the …

Oroxylum indicum (L.) Kurz, an important Asian traditional medicine: from traditional uses to scientific data for its commercial exploitation

B Dinda, I SilSarma, M Dinda, P Rudrapaul - Journal of …, 2015 - Elsevier
Ethnopharmacological relevance Oroxylum indicum\(L.) Kurz has been used for centuries as
a traditional medicine in Asia in ethnomedicinal systems for the prevention and treatment of …

Oroxylin A has therapeutic potential in acute myelogenous leukemia by dual effects targeting PPARγ and RXRα

H Hui, Y Chen, H Yang, K Zhao, Q Wang… - … journal of cancer, 2014 - Wiley Online Library
Oroxylin A (OA) is a flavonoid derived from a Chinese herb that has previously been
reported to inhibit the proliferation of several cancer cell lines. It is found that OA significantly …

Therapeutic potential of oridonin and its analogs: from anticancer and antiinflammation to neuroprotection

J Xu, EA Wold, Y Ding, Q Shen, J Zhou - Molecules, 2018 - mdpi.com
Oridonin, a diterpenoid natural product commonly used in East Asian herbal medicine, is
garnering increased attention in the biomedical community due to its extensive biological …

Antioxidant activity of γ-oryzanol: a complex network of interactions

IO Minatel, FV Francisqueti, CR Corrêa… - International journal of …, 2016 - mdpi.com
γ-oryzanol (Orz), a steryl ferulate extracted from rice bran layer, exerts a wide spectrum of
biological activities. In addition to its antioxidant activity, Orz is often associated with …

Therapeutic potentials of ononin with mechanistic insights: A comprehensive review

MS Bhuia, MA Aktar, R Chowdhury, J Ferdous… - Food Bioscience, 2023 - Elsevier
Ononin is a naturally occurring isoflavone glycoside generally found in various plants like
soybeans, legumes, Chinese licorice, Mongolian milkvetch, kudzu, broccoli, and lupine. The …

Oroxylin A exerts anti-inflammatory activity on lipopolysaccharide-induced mouse macrophage via Nrf2/ARE activation

M Ye, Q Wang, W Zhang, Z Li… - Biochemistry and Cell …, 2014 - cdnsciencepub.com
Regulating inflammation could be an important measure for the effective treatment of cancer.
Here we examine the mechanisms by which oroxylin A inhibits inflammation in RAW264. 7 …