Y Lu, W Huang, M Li, A Zheng - Pharmaceutics, 2023 - mdpi.com
In the last few decades, RNA-based drugs have emerged as a promising candidate to specifically target and modulate disease-relevant genes to cure genetic defects. The key to …
All forms of life produce nanosized extracellular vesicles called exosomes, which are enclosed in lipid bilayer membranes. Exosomes engage in cell-to-cell communication and …
Nanocarriers as drug/biomolecule delivery systems have been significantly developed during recent decades. Given the stability, reasonable delivery efficiency, and safety of …
XC Jiang, JQ Gao - International journal of pharmaceutics, 2017 - Elsevier
Clinical treatments have stalled in certain diseases due to a lack of proper therapeutic delivery systems. Recent studies have identified exosomes for their potential use as cell-free …
Application of exosomes, natural nanoscale vesicles, as specific delivery vehicles has received considerable attention in recent past years. The presence of various adhesive …
AJ O'Loughlin, CA Woffindale… - Current gene …, 2012 - ingentaconnect.com
Exosomes are a subtype of membrane vesicle released from the endocytic compartment of live cells. They play an important role in endogenous cell-to-cell communication. Previously …
Exosomes denote a class of secreted nanoparticles defined by size, surface protein and lipid composition, and the ability to carry RNA and proteins. They are important mediators of …
Simple Summary Exosomes derived from various sources can deliver therapeutic agents such as small molecule drugs, nucleic acids, and proteins to cancer cells by passive or …
C Lässer - Expert opinion on biological therapy, 2012 - Taylor & Francis
Introduction: Exosomes are nano-sized (40–100 nm), extracellular vesicles, of endosomal origin. They are released by cells and found in many body fluids, including plasma …