[HTML][HTML] Recent advances in exosome-mediated nucleic acid delivery for cancer therapy

Y Zhang, Q Liu, X Zhang, H Huang, S Tang… - Journal of …, 2022 - Springer
Cancer is a leading public health problem worldwide. Its treatment remains a daunting
challenge, although significant progress has been made in existing treatments in recent …

[HTML][HTML] Exosome-based carrier for RNA delivery: progress and challenges

Y Lu, W Huang, M Li, A Zheng - Pharmaceutics, 2023 - mdpi.com
In the last few decades, RNA-based drugs have emerged as a promising candidate to
specifically target and modulate disease-relevant genes to cure genetic defects. The key to …

[HTML][HTML] A comprehensive review on the composition, biogenesis, purification, and multifunctional role of exosome as delivery vehicles for cancer therapy

J Li, Y Zhang, PY Dong, GM Yang… - Biomedicine & …, 2023 - Elsevier
All forms of life produce nanosized extracellular vesicles called exosomes, which are
enclosed in lipid bilayer membranes. Exosomes engage in cell-to-cell communication and …

[HTML][HTML] Exosomes as bio-inspired nanocarriers for RNA delivery: preparation and applications

A Amiri, R Bagherifar, E Ansari Dezfouli… - Journal of Translational …, 2022 - Springer
Nanocarriers as drug/biomolecule delivery systems have been significantly developed
during recent decades. Given the stability, reasonable delivery efficiency, and safety of …

Exosomes as novel bio-carriers for gene and drug delivery

XC Jiang, JQ Gao - International journal of pharmaceutics, 2017 - Elsevier
Clinical treatments have stalled in certain diseases due to a lack of proper therapeutic
delivery systems. Recent studies have identified exosomes for their potential use as cell-free …

Exosomes: natural nanoparticles as bio shuttles for RNAi delivery

SG Darband, M Mirza-Aghazadeh-Attari… - Journal of Controlled …, 2018 - Elsevier
Application of exosomes, natural nanoscale vesicles, as specific delivery vehicles has
received considerable attention in recent past years. The presence of various adhesive …

Exosomes and the emerging field of exosome-based gene therapy

AJ O'Loughlin, CA Woffindale… - Current gene …, 2012 - ingentaconnect.com
Exosomes are a subtype of membrane vesicle released from the endocytic compartment of
live cells. They play an important role in endogenous cell-to-cell communication. Previously …

A comprehensive overview of exosomes as drug delivery vehicles—endogenous nanocarriers for targeted cancer therapy

KB Johnsen, JM Gudbergsson, MN Skov… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Exosomes denote a class of secreted nanoparticles defined by size, surface protein and
lipid composition, and the ability to carry RNA and proteins. They are important mediators of …

[HTML][HTML] Recent advances in exosome-based drug delivery for cancer therapy

H Kim, H Jang, H Cho, J Choi, KY Hwang, Y Choi… - Cancers, 2021 - mdpi.com
Simple Summary Exosomes derived from various sources can deliver therapeutic agents
such as small molecule drugs, nucleic acids, and proteins to cancer cells by passive or …

Exosomal RNA as biomarkers and the therapeutic potential of exosome vectors

C Lässer - Expert opinion on biological therapy, 2012 - Taylor & Francis
Introduction: Exosomes are nano-sized (40–100 nm), extracellular vesicles, of endosomal
origin. They are released by cells and found in many body fluids, including plasma …