Interleukin 6 in cerebrospinal fluid is a biomarker for delayed cerebral ischemia (DCI) related infarctions after aneurysmal subarachnoid hemorrhage

S Ridwan, A Grote, M Simon - Scientific Reports, 2021 - nature.com
Abstract Interleukin 6 (IL-6) is a prominent proinflammatory cytokine and has been
discussed as a potential biomarker for delayed cerebral ischemia (DCI) following …

Relevance of cerebral interleukin-6 after aneurysmal subarachnoid hemorrhage

A Sarrafzadeh, F Schlenk, C Gericke, P Vajkoczy - Neurocritical care, 2010 - Springer
Background This study examines the inflammatory response via interleukin-6 (IL-6) in
aneurysmal subarachnoid hemorrhage (aSAH) patients and its association with their clinical …

Interleukin 6 and aneurysmal subarachnoid hemorrhage. A narrative review

M Simon, A Grote - International Journal of Molecular Sciences, 2021 - mdpi.com
Interleukin 6 (IL-6) is a prominent proinflammatory cytokine. Neuroinflammation in general,
and IL-6 signaling in particular, appear to play a major role in the pathobiology and …

Early dynamics of interleukin-6 in cerebrospinal fluid after aneurysmal subarachnoid hemorrhage

K Ďuriš, E Neuman, V Vybíhal, V Juráň… - … Surgery Part A …, 2018 - thieme-connect.com
Background Subarachnoid hemorrhage (SAH) is a severe condition associated with high
mortality. Early brain injury (EBI) plays an important role in the pathophysiology of SAH, and …

Interleukin-6 as a prognostic biomarker in ruptured intracranial aneurysms

HW Kao, KW Lee, CL Kuo, CS Huang, WM Tseng… - PloS one, 2015 - journals.plos.org
Background Interleukin-6 (IL-6), a proinflammatory cytokine, was found to surge in the
cerebral spinal fluid after aneurysmal subarachnoid hemorrhage (SAH). We hypothesized …

High ICP as trigger of proinflammatory IL-6 cytokine activation in aneurysmal subarachnoid hemorrhage

D Graetz, A Nagel, F Schlenk, O Sakowitz… - Neurological …, 2010 - Taylor & Francis
Objective: There is a rising debate about the role of inflammation in the pathogenesis of
complications after aneurysmal subarachnoid hemorrhage (SAH) such as intracranial …

Interleukin-6, MCP-1, IP-10, and MIG are sequentially expressed in cerebrospinal fluid after subarachnoid hemorrhage

A Niwa, K Osuka, T Nakura, N Matsuo… - Journal of …, 2016 - Springer
Abstract Background Interleukin-6 (IL-6), an inflammatory cytokine, plays important roles in
cerebrospinal fluid (CSF) after subarachnoid hemorrhage (SAH). Chemokines are …

Point-of-care testing for interleukin-6 in cerebro spinal fluid (CSF) after subarachnoid haemorrhage.

J Dengler, JC Schefold, D Graetz, C Meisel… - … medical journal of …, 2008 - europepmc.org
Background Intrathecal interleukin (IL)-6 is considered to be a proinflammatory biomarker for
cerebral inflammatory response. This is of clinical importance for the prediction of …

The relationship between IL-6 in CSF and occurrence of vasospasm after subarachnoid hemorrhage

W Ni, YX Gu, DL Song, B Leng, PL Li, Y Mao - Early Brain Injury or …, 2011 - Springer
Background: It is hypothesized that inflammatory response after subarachnoid hemorrhage
(SAH) may play a relevant role in the development and maintenance of vasospasm. This …

Interleukin 6 in the cerebrospinal fluid as a biomarker for onset of vasospasm and ventriculitis after severe subarachnoid hemorrhage

M Lenski, V Huge, J Briegel, JC Tonn, C Schichor… - World neurosurgery, 2017 - Elsevier
Objective The aim of the study was to investigate the diagnostic potential of interleukin 6 (IL-
6) and other soluble biomarkers in serum and cerebrospinal fluid (CSF) for early diagnosis …