[PDF][PDF] Heterologous protein production and delivery systems for Lactococcus lactis

S Nouaille, LA Ribeiro, A Miyoshi, D Pontes… - Genet Mol …, 2003 - researchgate.net
Lactic acid bacteria (LAB), widely used in the food industry, are present in the intestine of
most animals, including humans. The potential use of these bacteria as live vehicles for the …

Lactococcus lactis as a live vector: heterologous protein production and DNA delivery systems

DS Pontes, MSP De Azevedo, JM Chatel… - Protein expression and …, 2011 - Elsevier
Lactic acid bacteria (LAB), widely used in the food industry, are present in the intestine of
most animals, including humans. The potential use of these bacteria as mucosal delivery …

Lactococcus lactis as a cell factory for delivery of therapeutic proteins

M Bahey-El-Din, CGM Gahan, BT Griffin - Current gene therapy, 2010 - ingentaconnect.com
The food-grade bacterium Lactococcus lactis has been extensively investigated during the
last two decades as a delivery vector for therapeutic proteins, DNA and vaccine antigens …

Lactococcus lactis as a live vector for mucosal delivery of therapeutic proteins

LG Bermúdez-Humarán - Human vaccines, 2009 - Taylor & Francis
Food-grade lactic acid bacteria (LAB) have been safely consumed by humans for centuries
in fermented foods. Lactococcus lactis, a LAB widely used in the dairy industry as a starter …

Lactococci and lactobacilli as mucosal delivery vectors for therapeutic proteins and DNA vaccines

LG Bermúdez-Humarán, P Kharrat, JM Chatel… - Microbial cell …, 2011 - Springer
Abstract Food-grade Lactic Acid Bacteria (LAB) have been safely consumed for centuries by
humans in fermented foods. Thus, they are good candidates to develop novel oral vectors …

Engineering lactococci and lactobacilli for human health

LG Bermúdez-Humarán, C Aubry, JP Motta… - Current opinion in …, 2013 - Elsevier
Highlights•Recombinant lactococci and lactobacilli have been successfully used in the last
years as safe mucosal delivery vectors for molecules of health interest.•The delivery of …

Lactic acid bacteria—20 years exploring their potential as live vectors for mucosal vaccination

A Wyszyńska, P Kobierecka, J Bardowski… - Applied microbiology …, 2015 - Springer
Lactic acid bacteria (LAB) are a diverse group of Gram-positive, nonsporulating, low G+ C
content bacteria. Many of them have been given generally regarded as safe status. Over the …

Lactic acid bacteria as live vaccines

A Mercenier, H Müller-Alouf, C Grangette - Current issues in molecular …, 2000 - mdpi.com
Mucosal routes for vaccine delivery offer several advantages over systemic inoculation from
both immunological and practical points of view. The development of efficient mucosal …

Heterologous protein secretion in Lactococcus lactis: a novel antigen delivery system

P Langella, Y Le Loir - Brazilian journal of medical and biological …, 1999 - SciELO Brasil
Lactic acid bacteria (LAB) are Gram-positive bacteria and are generally regarded as safe
(GRAS) organisms. Therefore, LAB could be used for heterologous protein secretion and …

Lactic acid bacteria as mucosal delivery vehicles: a realistic therapeutic option

M Wang, Z Gao, Y Zhang, L Pan - Applied microbiology and biotechnology, 2016 - Springer
Recombinant lactic acid bacteria (LAB), in particular lactococci and lactobacilli, have gained
increasing interest as mucosal delivery vehicles in recent years. With the development of …