Investigational pharmacological agents for the treatment of ARDS

K Aribindi, M Lim, S Lakshminrusimha… - Expert Opinion on …, 2024 - Taylor & Francis
ABSTRACT Introduction Acute Respiratory Distress Syndrome (ARDS) is a heterogeneous
form of lung injury with severe hypoxemia and bilateral infiltrates after an inciting event that …

Emerging pharmacological therapies for ARDS: COVID-19 and beyond

S Horie, B McNicholas, E Rezoagli, T Pham… - Intensive care …, 2020 - Springer
ARDS, first described in 1967, is the commonest form of acute severe hypoxemic respiratory
failure. Despite considerable advances in our knowledge regarding the pathophysiology of …

Prospects of Novel and Repurposed Immunomodulatory Drugs against Acute Respiratory Distress Syndrome (ARDS) Associated with COVID-19 Disease

SS Nayak, A Naidu, SL Sudhakaran, S Vino… - Journal of personalized …, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is intricately linked with SARS-CoV-2-
associated disease severity and mortality, especially in patients with co-morbidities. Lung …

Recent progress and prospects for anti-cytokine therapy in preclinical and clinical acute lung injury

GP Fadanni, JB Calixto - Cytokine & Growth Factor Reviews, 2023 - Elsevier
Acute respiratory distress syndrome (ARDS) is a heterogeneous cause of respiratory failure
that has a rapid onset, a high mortality rate, and for which there is no effective …

Acute respiratory distress syndrome in COVID-19: possible mechanisms and therapeutic management

A Aslan, C Aslan, NM Zolbanin, R Jafari - Pneumonia, 2021 - Springer
COVID-19 pandemic is a serious concern in the new era. Acute respiratory distress
syndrome (ARDS), and lung failure are the main lung diseases in COVID-19 patients. Even …

COVID-19-related ARDS: key mechanistic features and treatments

J Selickman, CS Vrettou, SD Mentzelopoulos… - Journal of clinical …, 2022 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome historically
characterized by the presence of severe hypoxemia, high-permeability pulmonary edema …

Current practice review in the management of acute respiratory distress syndrome

MB Chudow, MS Condeni, S Dhar… - Journal of …, 2023 - journals.sagepub.com
Acute respiratory distress syndrome (ARDS) presents as an acute inflammatory lung injury
characterized by refractory hypoxemia and non-cardiac pulmonary edema. An estimated …

Applying lessons learned from COVID-19 therapeutic trials to improve future ALI/ARDS trials

Q Wu, ME Pennini, JN Bergmann… - Open forum …, 2022 - academic.oup.com
Host-directed therapeutics targeting immune dysregulation are considered the most
promising approach to address the unmet clinical need for acute lung injury (ALI)/acute …

Acute respiratory distress syndrome and COVID-19: A literature review

M Hussain, S Khurram Syed, M Fatima… - Journal of …, 2021 - Taylor & Francis
Acute respiratory distress syndrome (ARDS) is an overwhelming inflammatory disorder of
the lung due to direct and indirect insults to the lungs. ARDS is characterized by increased …

Promising Treatments for Acute Respiratory Distress Syndrome Associated with Covid-19

MB Mezanini, MM de Souza… - Journal of Modern …, 2022 - synergypublishers.com
Abstract Acute Respiratory Distress Syndrome (ARDS) can occur in critically ill people due
to COVID-19. These combinations of ARDS and COVID-19 are usually fatal, and the risk …