[HTML][HTML] Potential role of IFN-α in COVID-19 patients and its underlying treatment options
Abstract The coronavirus disease (COVID-19) caused by a severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly worldwide. Given that this …
syndrome coronavirus 2 (SARS-CoV-2) has spread rapidly worldwide. Given that this …
Interferon β, an enhancer of the innate immune response against SARS-CoV-2 infection
COVID-19 exhibits a global health threat among the elderly and the population with
underlying health conditions. During infection, the host's innate immune response acts as a …
underlying health conditions. During infection, the host's innate immune response acts as a …
Type-I interferons in the immunopathogenesis and treatment of Coronavirus disease 2019
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease 2019 (COVID-19), is currently the major global health problem. Still, it …
coronavirus disease 2019 (COVID-19), is currently the major global health problem. Still, it …
[HTML][HTML] Interferon at the crossroads of SARS-CoV-2 infection and COVID-19 disease
CE Samuel - Journal of Biological Chemistry, 2023 - ASBMB
A novel coronavirus now known as SARS-CoV-2 emerged in late 2019, possibly following a
zoonotic crossover from a coronavirus present in bats. This virus was identified as the …
zoonotic crossover from a coronavirus present in bats. This virus was identified as the …
Type I IFNs: A blessing in disguise or partner in crime in MERS-CoV-, SARS-CoV-, and SARS-CoV-2-Induced pathology and potential use of type I IFNs in synergism …
Since the end of 2019, the emergence of novel coronavirus disease 2019 (COVID-19)
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has accelerated …
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has accelerated …
[HTML][HTML] Roles of Type I and III Interferons in COVID-19
Abstract Coronavirus disease 2019 (COVID-19) is an ongoing global pandemic caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Type I and III interferon …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Type I and III interferon …
[HTML][HTML] Correlation between type I interferon associated factors and COVID-19 severity
D Bencze, T Fekete, K Pázmándi - International Journal of Molecular …, 2022 - mdpi.com
Antiviral type I interferons (IFN) produced in the early phase of viral infections effectively
inhibit viral replication, prevent virus-mediated tissue damages and promote innate and …
inhibit viral replication, prevent virus-mediated tissue damages and promote innate and …
[HTML][HTML] Type I IFN deficiency: an immunological characteristic of severe COVID-19 patients
Z Wang, H Pan, B Jiang - Signal Transduction and Targeted Therapy, 2020 - nature.com
Recently, a paper published in Science by Hadjadj et al. reported that type I interferon (IFN)
deficiency, could be a hallmark of severe coronavirus disease 2019 (COVID-19) caused by …
deficiency, could be a hallmark of severe coronavirus disease 2019 (COVID-19) caused by …
[HTML][HTML] Interferon-α2b Treatment for COVID-19
Q Zhou, V Chen, CP Shannon, XS Wei… - Frontiers in …, 2020 - frontiersin.org
The global pandemic of COVID-19 cases caused by infection with SARS-CoV-2 is ongoing,
with no approved antiviral intervention. We describe here the effects of treatment with …
with no approved antiviral intervention. We describe here the effects of treatment with …
COVID‐19: lambda interferon against viral load and hyperinflammation
E Andreakos, S Tsiodras - EMBO molecular medicine, 2020 - embopress.org
Coronavirus disease 2019 (COVID‐19), triggered by the betacoronavirus SARS‐CoV‐2, has
become one of the worst pandemics of our time that has already caused more than 250,000 …
become one of the worst pandemics of our time that has already caused more than 250,000 …