The beneficial effects of metformin on cancer prevention and therapy: a comprehensive review of recent advances

P Saraei, I Asadi, MA Kakar… - Cancer management and …, 2019 - Taylor & Francis
Metformin is a widely used drug in today's prescriptions by physicians due to its specific
effects in treating and curing type II diabetes. Diabetes is a common disease that may occur …

Metformin: A promising drug for human cancers

H Wu, D Huang, H Zhou, X Sima, Z Wu… - Oncology …, 2022 - spandidos-publications.com
Small‑molecule chemical drugs are of great significance for tumor‑targeted and
individualized therapies. However, the development of new small‑molecule drugs, from …

Anti-cancer effects of metformin: recent evidences for its role in prevention and treatment of cancer

M Kheirandish, H Mahboobi… - Current Drug …, 2018 - ingentaconnect.com
Background: Metformin is widely used for management of Type 2 Diabetes Mellitus (T2DM).
Recently growing evidences have shown its anti-cancer effects. The results are mainly from …

Investigating metformin for cancer prevention and treatment: the end of the beginning

MN Pollak - Cancer discovery, 2012 - AACR
Laboratory research and pharmacoepidemiology are providing converging evidence that
the widely used antidiabetic drug metformin has antineoplastic activity, but there are …

Metformin in cancer treatment and prevention

DR Morales, AD Morris - Annual review of medicine, 2015 - annualreviews.org
Patients with diabetes mellitus are at increased risk of cancer development. Metformin is a
well-established, effective agent for the management of type 2 diabetes mellitus …

Metformin: a novel but controversial drug in cancer prevention and treatment

X Sui, Y Xu, X Wang, W Han, H Pan… - Molecular …, 2015 - ACS Publications
Metformin, a biguanide derivative that is widely used for treating type 2 diabetes mellitus,
has recently been shown to exert potential anticancer effects. Many retrospective data and …

Metformin and cancer: An existing drug for cancer prevention and therapy

F Zi, H Zi, Y Li, J He, Q Shi, Z Cai - Oncology letters, 2018 - spandidos-publications.com
Metformin is a standard clinical drug used to treat type 2 diabetes mellitus (T2DM) and
polycystic ovary syndrome. Recently, epidemiological studies and meta‑analyses have …

Anticancer activity of metformin: a systematic review of the literature

M Aljofan, D Riethmacher - Future science OA, 2019 - Taylor & Francis
Background: The anticancer activity of metformin has been confirmed against several cancer
types in vitro and in vivo. However, the underlying mechanisms of metformin in the treatment …

Metformin intervention—a panacea for cancer treatment?

A Buczyńska, I Sidorkiewicz, AJ Krętowski… - Cancers, 2022 - mdpi.com
Simple Summary This literature analysis is focused on the pleiotropic action associated with
metformin treatment. Precisely, metformin treatment exerts many health effects, mainly by …

[HTML][HTML] Metformin in cancer prevention and therapy

J Kasznicki, A Sliwinska, J Drzewoski - Annals of translational …, 2014 - ncbi.nlm.nih.gov
The prevalence of diabetes is dramatically increasing worldwide. The results of numerous
epidemiological studies indicate that diabetic population is not only at increased risk of …