Epigenetic regulations, such as DNA methylation and microRNAs, play an important role in
renal fibrosis. Here, we report the regulation of microRNA-219a-2 (mir-219a-2) by DNA …

Progressive renal fibrosis is the last phase of chronic kidney disease and results in renal
failure. Micro-RNA has been demonstrated as important agent to drive organ fibrosis …

Scarring of the kidney directly promotes loss of kidney function. A thorough understanding of
renal fibrosis at the molecular level is urgently needed. One prominent microRNA, miR-21 …

The role of exogenous microRNAs (miRNAs) in renal fibrosis is poorly understood. Here, the
effect of exogenous miRNAs on renal fibrosis was investigated using a renal fibrosis mouse …

Background/Aims: Renal interstitial fibrosis (RIF) is a common feature that facilitates the
progression of chronic kidney disease (CKD), and emerging lines of evidence suggest that …

MicroRNAs (miRNAs) regulate gene expression post-transcriptionally and control biological
processes, including fibrogenesis. Kidney fibrosis remains a clinical challenge and miRNAs …

Abstract Although microRNA‐155 (miR‐155) is implicated in the pathogenesis of several
fibrotic diseases, information regarding its functional role in renal fibrosis is limited. The …

Renal fibrosis induced by urinary tract obstruction is a common clinical occurrence;
however, effective treatment is lacking, and a deeper understanding of the mechanism of …

Renal fibrosis is associated with the reduction in the functional renal parenchyma and in
most cases progresses to end-stage kidney failure, a devastating condition that requires …

Abstract micro RNAs (miRNAs) are small non-coding RNAs that act as posttranscriptional
repressors by binding to the 3′-UTR of target mRNAs. On the other hand, mesenchymal …