Lupus nephritis (LN) is a major cause of morbidity and mortality in systemic lupus
erythematosus (SLE). The mechanisms of renal damage are complex. LN is characterized …

Publisher Summary Renal disease ranks as the foremost cause of morbidity and mortality in
systemic lupus erythematosus (SLE). Although several different end organs can be targeted …

Lupus nephritis (LN) is clinically evident in 50 to 75% of patients with systemic lupus
erythematosus and is a significant cause of ESRD. Although LN is a paradigmatic example …

Systemic lupus erythematosus (SLE) is an autoimmune disease of unknown cause that can
occur at almost any age, although it affects mostly women in their 20s. The annual incidence …

Lupus nephritis (LN) is a common and severe manifestation of systemic lupus
erythematosus (SLE). LN is a glomerulonephritis characterized by the accumulation of …

Immunosuppressive therapies for lupus nephritis (LN) have improved significantly over the
past few decades, resulting in growing number of choices for treatment individualization and …

Lupus nephritis contributes notably to the morbidity and mortality of systemic lupus
erythematosus. Improved medical therapies have increased the median survival of patients …

Lupus nephritis (LN) is a frequent and serious complication of systemic lupus erythematosus
(SLE), impairing patients' quality of life and significantly increasing mortality. Despite …

Lupus nephritis (LN) is clinically evident in 50–75% of lupus patients and is a significant
cause of end-stage renal disease. Although LN is a paradigm of immune complex–mediated …

Of all the organ domains involved in systemic lupus ery-thematosus (SLE), renal disease is
associated with the greatest morbidity and mortality. Relative age-adjusted mortality in SLE …