Trafficking and other regulatory mechanisms for organic anion transporting polypeptides and organic anion transporters that modulate cellular drug and xenobiotic …
M Murray, F Zhou - British journal of pharmacology, 2017 - Wiley Online Library
Organic anion transporters (OATs) and organic anion‐transporting polypeptides (OATPs),
encoded by a number of solute carrier (SLC) 22A and SLC organic anion (SLCO) genes …
encoded by a number of solute carrier (SLC) 22A and SLC organic anion (SLCO) genes …
Post-translational regulation of the major drug transporters in the families of organic anion transporters and organic anion–transporting polypeptides
W Lee, J Ha, Y Sugiyama - Journal of Biological Chemistry, 2020 - ASBMB
The organic anion transporters (OATs) and organic anion–transporting polypeptides
(OATPs) belong to the solute carrier (SLC) transporter superfamily and play important roles …
(OATPs) belong to the solute carrier (SLC) transporter superfamily and play important roles …
Organic anion‐transporting polypeptides
RG Tirona, RB Kim - Drug Transporters: Molecular …, 2014 - Wiley Online Library
This chapter begins with a review of the organic anion‐transporting polypeptides (OATPs)
superfamily nomenclature followed by sections covering molecular characteristics, aspects …
superfamily nomenclature followed by sections covering molecular characteristics, aspects …
The role of organic anion transporting polypeptides in drug absorption, distribution, excretion and drug-drug interactions
D Kovacsics, I Patik… - Expert opinion on drug …, 2017 - Taylor & Francis
Introduction: The in vivo fate and effectiveness of a drug depends highly on its absorption,
distribution, metabolism, excretion and toxicity (ADME-Tox). Organic anion transporting …
distribution, metabolism, excretion and toxicity (ADME-Tox). Organic anion transporting …
Xenobiotic transporters of the human organic anion transporting polypeptides (OATP) family
B Hagenbuch, C Gui - Xenobiotica, 2008 - Taylor & Francis
1. The organic anion transporting polypeptides (humans OATP; other species Oatp) belong
to the SLCO gene superfamily of transporters and are twelve transmembrane domain …
to the SLCO gene superfamily of transporters and are twelve transmembrane domain …
Organic anion-transporting polypeptides
B Stieger, B Hagenbuch - Current topics in membranes, 2014 - Elsevier
Organic anion-transporting polypeptides or OATPs are central transporters in the disposition
of drugs and other xenobiotics. In addition, they mediate transport of a wide variety of …
of drugs and other xenobiotics. In addition, they mediate transport of a wide variety of …
Uptake transporters of the human OATP family: molecular characteristics, substrates, their role in drug–drug interactions, and functional consequences of …
J König - Drug Transporters, 2011 - Springer
Organic anion transporting polypeptides (OATPs, gene family: SLC21/SLCO) mediate the
uptake of a broad range of substrates including several widely prescribed drugs into cells …
uptake of a broad range of substrates including several widely prescribed drugs into cells …
Regulation of organic anion transporting polypeptides (OATP) 1B1-and OATP1B3-mediated transport: an updated review in the context of OATP-mediated drug-drug …
Organic anion transporting polypeptides (OATP) 1B1 and OATP1B3 are important hepatic
transporters that mediate the uptake of many clinically important drugs, including statins from …
transporters that mediate the uptake of many clinically important drugs, including statins from …
OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies
M Roth, A Obaidat, B Hagenbuch - British journal of …, 2012 - Wiley Online Library
The human organic anion and cation transporters are classified within two SLC
superfamilies. Superfamily SLCO (formerly SLC21A) consists of organic anion transporting …
superfamilies. Superfamily SLCO (formerly SLC21A) consists of organic anion transporting …
Amino acid residues in the putative transmembrane domain 11 of human organic anion transporting polypeptide 1B1 dictate transporter substrate binding, stability …
Organic anion transporting polypeptides (OATPs, gene symbol SLCO) are membrane
proteins that mediate the sodium-independent transport of a wide range of endogenous and …
proteins that mediate the sodium-independent transport of a wide range of endogenous and …