Even though many useful tools for sequence alignment are available, such as BLAST and
PSI-BLAST by NCBI and FASTA by the University of Virginia, a key issue regarding …

In spite of the existence of several grid middleware projects, developing and executing
programs on the computational grid remains a user intensive process. The goal of the Grid …

Motivation: Grid computing is used to solve large-scale bioinformatics problems with
gigabytes database by distributing the computation across multiple platforms. Untill now in …

Abstract The Basic Local Alignment Search Tool (BLAST) is one of the best known
sequence comparison programs available in bioinformatics. It is used to compare query …

BLASTZ is a sequence alignment tool designed mainly for aligning neutrally evolved bio-
sequences and has been the choice for aligning noncoding sequences. However, its …

Background There is an increasing demand to assemble and align large-scale biological
sequence data sets. The commonly used multiple sequence alignment programs are still …

Over the past few years, research and development in bioinformatics (eg genomic sequence
alignment) has grown with each passing day fueling continuing demands for vast computing …

In the last decade, we have observed an unprecedented development in molecular biology.
An extremely high number of organisms have been sequenced in genome projects and …

Abstract Development of high-throughput technologies, such as Next-generation
sequencing, allows thousands of experiments to be performed simultaneously while …

In this paper, we propose an adaptive task allocation framework to perform BLAST searches
in a grid environment against sequence database segments. The framework, called …