Nitrates and left ventricular remodeling

BI Jugdutt - The American journal of cardiology, 1998 - Elsevier
Left ventricular remodeling is the major mechanism leading to cardiac enlargement, failure,
and death after myocardial infarction. It is associated with early disruption of collagen matrix …

Role of nitrates after acute myocardial infarction

BI Jugdutt - The American journal of cardiology, 1992 - Elsevier
Apart from their ability to relieve myocardial ischemia, nitrates have an important role to play
on preservation of left ventricular (LV) geometry and function after acute myocardial …

Effect of nitrates on myocardial remodeling after acute myocardial infarction

BI Jugdutt - The American journal of cardiology, 1996 - Elsevier
Nitrates are effective for the therapy of acute coronary syndromes, including acute
myocardial infarction. Their application in acute infarction has established that vasodilators …

Nitric oxide and cardiac remodeling

J Passeri, KD Bloch - Heart Failure Clinics, 2005 - heartfailure.theclinics.com
The term ventricular remodeling was first applied to changes in the left ventricle, including
dilation and hypertrophy, that occur after myocardial infarction to preserve cardiac output …

Does nitric oxide contribute to progressive cardiac tissue damage and dysfunction after infarction?

C Berthonneche, MC Toufektsian, S Tanguy… - Antioxidants & redox …, 2007 - liebertpub.com
Myocardial infarction induces contractile dysfunction and remodeling that can lead to heart
failure. Nitric oxide has been proposed as one of the major actors of this pathophysiologic …

Effects of nitrate therapy on ventricular remodeling and function

BI Jugdutt - The American journal of cardiology, 1993 - Elsevier
The hypothesis that nitrates might effectively limit left ventricular remodeling and improve
function after acute myocardial infarction has been tested in experimental and clinical …

Low-dose sodium nitrite attenuates myocardial ischemia and vascular ischemia-reperfusion injury in human models

TE Ingram, AG Fraser, RA Bleasdale, EA Ellins… - Journal of the American …, 2013 - jacc.org
Objectives: The aim of this study was to assess the potential benefits of inorganic nitrite in 2
clinical models: stress-induced myocardial ischemia and whole-arm ischemia-reperfusion …

Long-term oral nitrate therapy prevents chronic ventricular remodeling in the dog

KM McDonald, GS Francis, J Matthews… - Journal of the American …, 1993 - Elsevier
Objectives. The purpose of this experiment was to assess the long-term effects of oral nitrate
therapy on ventricular remodeling in a canine model of discrete myocardial damage …

Nitrite and myocardial ischaemia reperfusion injury. Where are we now?

K Griffiths, JJ Lee, MP Frenneaux, M Feelisch… - Pharmacology & …, 2021 - Elsevier
Cardiovascular disease remains the leading cause of death worldwide despite major
advances in technology and treatment, with coronary heart disease (CHD) being a key …

Effect of prolonged nitrate therapy on left ventricular remodeling after canine acute myocardial infarction.

BI Jugdutt, MI Khan - Circulation, 1994 - Am Heart Assoc
BACKGROUND Prolonged nitrate therapy during healing between 2 days and 6 weeks after
anterior myocardial infarction has the potential for limiting further left ventricular remodeling …