High-throughput experimentation for chemistry and chemical biology has emerged as a
highly impactful technology, particularly when applied to Direct-to-Biology. Analysis of the …

Conspectus The incorporation of data science is revolutionizing organic chemistry. It is
becoming increasingly possible to predict reaction outcomes with accuracy, computationally …

We herein describe the development and application of a modular technology platform
which incorporates recent advances in plate-based microscale chemistry, automated …

The Purdue Make It system is a unique automated platform capable of small-scale in situ
synthesis, screening small-molecule reactions, and performing direct label-free bioassays …

Automated chemistry platforms have been widely explored, but many focus on fixed tasks for
chemical synthesis or analysis. However, a typical synthetic chemistry workflow utilizes both …

Recent literature suggests that the fields of machine learning (ML) and high-throughput
experimentation (HTE) have separately received considerable attention from chemists and …

High-throughput experimentation (HTE) is a well-established technique used in the
pharmaceutical industry to accelerate compound synthesis and route optimization through …

Automation and digitalization solutions in the field of small molecule synthesis face new
challenges for chemical reaction analysis, especially in the field of high-performance liquid …

High throughput experimentation is a growing and evolving field that allows to execute
dozens to several thousands of experiments per day with relatively limited resources …

Automation and real-time reaction monitoring have enabled data-rich experimentation,
which is critically important in navigating the complexities of chemical synthesis. Linking real …