Microenvironment-Sensitive Nanozymes for Tissue Regeneration

Y Xiong, B Mi, G Liu, Y Zhao - Biomaterials, 2024 - Elsevier
Tissue defect is one of the significant challenges encountered in clinical practice.
Nanomaterials, including nanoparticles, nanofibers, and metal-organic frameworks, have …

[HTML][HTML] Unraveling the potential of nanozymes in the tapestry of orthopedic healing

J Yu, H Jiang, H Shen, L Zhu, X Xue, J Lin, J Wang… - Materials & Design, 2024 - Elsevier
Bone-related disorders, such as osteoporosis, osteoarthritis, and osteosarcoma, have
complex origins. Genetic, environmental factors, and significantly, oxidative stress due to …

Nanozyme-based remodeling of disease microenvironments for disease prevention and treatment: a review

Y Ju, X Liu, X Ye, M Dai, B Fang… - ACS Applied Nano …, 2023 - ACS Publications
Nanomaterials that can mimic the activity of various enzymes have been studied extensively
in the biomedical field in recent years. Nanozymes offer better stability and economic value …

Nanotechnology-driven therapeutic interventions in wound healing: potential uses and applications

S Hamdan, I Pastar, S Drakulich, E Dikici… - ACS central …, 2017 - ACS Publications
The chronic nature and associated complications of nonhealing wounds have led to the
emergence of nanotechnology-based therapies that aim at facilitating the healing process …

An Immunomodulatory Biomimetic Single‐Atomic Nanozyme for Biofilm Wound Healing Management

J Zhang, M Lv, X Wang, F Wu, C Yao, J Shen, N Zhou… - Small, 2023 - Wiley Online Library
Nanozyme‐driven catalytic antibacterial therapy has become a promising modality for
bacterial biofilm infections. However, current catalytic therapy of biofilm wounds is severely …

Nanozymes With Osteochondral Regenerative Effects: An Overview of Mechanisms and Recent Applications

X Sun, X Xu, X Yue, T Wang, Z Wang… - Advanced …, 2024 - Wiley Online Library
With the discovery of the intrinsic enzyme‐like activity of metal oxides, nanozymes garner
significant attention due to their superior characteristics, such as low cost, high stability, multi …

Mechanobiological strategies to enhance stem cell functionality for regenerative medicine and tissue engineering

M Shafiq, O Ali, SB Han, DH Kim - Frontiers in Cell and …, 2021 - frontiersin.org
Stem cells have been extensively used in regenerative medicine and tissue engineering;
however, they often lose their functionality because of the inflammatory microenvironment …

Nanomaterials, inflammation, and tissue engineering

J Padmanabhan, TR Kyriakides - … Reviews: Nanomedicine and …, 2015 - Wiley Online Library
Nanomaterials exhibit unique properties that are absent in the bulk material because
decreasing material size leads to an exponential increase in surface area, surface area to …

Nanozymes for regenerative medicine

X Mou, Q Wu, Z Zhang, Y Liu, J Zhang, C Zhang… - Small …, 2022 - Wiley Online Library
Nanozymes refer to nanomaterials that catalyze enzyme substrates into products under
relevant physiological conditions following enzyme kinetics. Compared to natural enzymes …

Nanomedicine in healing chronic wounds: opportunities and challenges

S Sharifi, MJ Hajipour, L Gould… - Molecular …, 2020 - ACS Publications
The poor healing associated with chronic wounds affects millions of people worldwide
through high mortality rates and associated costs. Chronic wounds present three main …