Immunoregulation in diabetic wound repair with a photoenhanced glycyrrhizic acid hydrogel scaffold

Y Qian, Y Zheng, J Jin, X Wu, K Xu, M Dai… - Advanced …, 2022 - Wiley Online Library
M1 macrophage accumulation and excessive inflammation are commonly encountered
issues in diabetic wounds and can fail in the healing process. Hence, hydrogel dressings …

Photo-crosslinked enhanced double-network hydrogels based on modified gelatin and oxidized sodium alginate for diabetic wound healing

B Cao, C Wang, P Guo, Q Zhang, C Wang… - International journal of …, 2023 - Elsevier
The diabetic wound is hard to repair due to bacterial infection, lasting inflammation, and so
on. Therefore, it is vital to fabricate a multi-functional hydrogel dressing for the diabetic …

Glycosaminoglycan-based hydrogel delivery system regulates the wound microenvironment to rescue chronic wound healing

X Zhang, J Feng, W Feng, B Xu, K Zhang… - … Applied Materials & …, 2022 - ACS Publications
Chronic wounds cannot proceed through the normal, orderly, and timely sequence of repair.
The adverse cycle between excess reactive oxide species (ROS) and a persistent …

Glycopeptide‐Based Multifunctional Hydrogels Promote Diabetic Wound Healing through pH Regulation of Microenvironment

H Xia, Z Dong, Q Tang, R Ding, Y Bai… - Advanced functional …, 2023 - Wiley Online Library
Excessive inflammation, bacterial infection, and blocked angiogenesis make diabetic wound
healing challenging. Multifunctional wound dressings have several advantages in diabetic …

Photopolymerizable, immunomodulatory hydrogels of gelatin methacryloyl and carboxymethyl chitosan as all-in-one strategic dressing for wound healing

S Ding, S He, K Ye, X Shao, Q Yang, G Yang - International Journal of …, 2023 - Elsevier
Microenvironment regeneration in wound tissue is crucial for wound healing. However,
achieving desirable wound microenvironment regeneration involves multiple stages …

pH and glucose dual-responsive injectable hydrogels with insulin and fibroblasts as bioactive dressings for diabetic wound healing

L Zhao, L Niu, H Liang, H Tan, C Liu… - ACS applied materials & …, 2017 - ACS Publications
pH and glucose dual-responsive injectable hydrogels were prepared through the cross-
linking of Schiff's base and phenylboronate ester using phenylboronic-modified chitosan …

An injectable photo-cross-linking silk hydrogel system augments diabetic wound healing in orthopaedic surgery through spatiotemporal immunomodulation

J Mei, J Zhou, L Kong, Y Dai, X Zhang, W Song… - Journal of …, 2022 - Springer
Background The complicated hyperglycaemic and chronic inflammation of diabetic wounds
in orthopaedic surgery leads to dysregulated immune cell function and potential infection …

Dual cross-linked organic-inorganic hybrid hydrogels accelerate diabetic skin wound healing

Y Qian, C Xu, W Xiong, N Jiang, Y Zheng, X He… - Chemical Engineering …, 2021 - Elsevier
Limited therapeutic options are available for healing chronic non-self-healing diabetic
wounds, which are characterized by bacterial infection as well as a hypoxic …

A dual‐cross‐linked hydrogel patch for promoting diabetic wound healing

J Liu, M Qu, C Wang, Y Xue, H Huang, Q Chen, W Sun… - Small, 2022 - Wiley Online Library
Diabetic wound treatment faces significant challenges in clinical settings. Alternative
treatment approaches are needed. Continuous bleeding, disordered inflammatory …

All‐Natural Immunomodulatory Bioadhesive Hydrogel Promotes Angiogenesis and Diabetic Wound Healing by Regulating Macrophage Heterogeneity

YJ Fu, YF Shi, LY Wang, YF Zhao, RK Wang… - Advanced …, 2023 - Wiley Online Library
Macrophages are highly heterogeneous and exhibit a diversity of functions and phenotypes.
They can be divided into pro‐inflammatory macrophages (M1) and anti‐inflammatory …