Population aging is one of the most important demographic transformations of our time.
Increasing the “health span”—the proportion of life spent in good health—is a global priority …

Cardiovascular disease (CVD) has increasing challenges for human health with an
increasingly aging population worldwide, imposing a significant obstacle to the goal of …

Aging is the main risk factor for vascular disease and ensuing cardiovascular and
cerebrovascular events, the leading causes of death worldwide. In a progressively aging …

The incidence of CVD and 50% 5-year mortality rate of heart failure have remained
unchanged for 2 decades (3). If the progression of CVD is not substantially prevented, the …

The prevalence of cardiovascular diseases markedly rises with age. Cellular senescence, a
hallmark of aging, is characterized by irreversible cell cycle arrest and the manifestation of a …

The manifestations of certain cardiovascular diseases that lead to heart failure and stroke,
such as atherosclerosis and hypertension, likely become altered in advanced age because …

Cardiovascular ageing is a process that begins early in life and leads to a progressive
change in structure and decline in function due to accumulated damage across diverse cell …

Cardiovascular diseases are the leading cause of death for population over 65 years of age.
With the progressive increase of population in this age group, it is crucial to understand the …

The age gap, also known as the difference between biological age and chronological age,
has long served as a conceptual framework for understanding age-related disease …

2 Lima Aging Human Heart studies involving individuals of similar age range enrolled in
MESA (Multiethnic Study of Atherosclerosis), in analyses that also excluded participants with …