Vitamin K is a fat-soluble vitamin that is indispensable for the activation of vitamin K-
dependent proteins (VKDPs) and may be implicated in cardiovascular disease (CVD) …

Vascular calcification, a cause of cardiovascular morbidity and mortality, is an actively
regulated process involving vitamin K dependent proteins (VKDPs) among others. Vitamin K …

With the discovery that vitamin K-dependent matrix Gla-protein (MGP) is a strong and
modifiable factor in the prevention of arterial calcification, vitamin K was put forward as novel …

Matrix gla protein (MGP) is an important vitamin K-dependent inhibitor of vascular
calcification. High levels of uncarboxylated, dephosphorylated MGP have been associated …

Chronic Kidney Disease (CKD) patients are at high risk of presenting with arterial
calcification or stiffness, which confers increased cardiovascular mortality and morbidity. In …

Matrix Gla Protein (MGP) is a strong vitamin K-dependent inhibitor of soft tissue calcification.
We assessed the prevalence of functional vitamin K insufficiency, as derived from plasma …

Specific patient cohorts are at increased risk of vascular calcification. Functional matrix-gla
protein (MGP), a tissue-derived vitamin K dependent protein, is reported to be an important …

Background Arterial calcification is associated with cardiovascular mortality in dialysis
patients. Active matrix Gla protein (MGP) is a vitamin K-dependent inhibitor of arterial …

Objectives The activity of matrix Gla-protein (MGP), a potent inhibitor of vascular
calcification, is dependent on carboxylation using vitamin K as a co-factor. In animals, low …

Vascular calcification occurs when calcium accumulates in the intima (associated with
atherosclerosis) and/or media layers of the vessel wall. Coronary artery calcification (CAC) …