Recent advances in the genetics of hypertension

LK Wei, A Au, LK Teh, HS Lye - … : from basic research to clinical practice, 2017 - Springer
Hypertension is a silent killer worldwide, caused by both genetic and environmental factors.
Until now, genetic and genomic association studies of hypertension are reporting different …

New developments in the genetics of hypertension: what should clinicians know?

DS Geller - Current cardiology reports, 2015 - Springer
It has long been known that genetic factors play a major role in determining an individual's
propensity to hypertension. In recent years, there has been major progress towards realizing …

Genetic determinants of blood pressure regulation

JB Marteau, M Zaiou, G Siest… - Journal of …, 2005 - journals.lww.com
Hypertension is a multifactorial disorder that probably results from the inheritance of a
number of susceptibility genes and involves multiple environmental determinants. Existing …

Genetic variations related to hypertension: a review

MOM Tanira, KA Al Balushi - Journal of human hypertension, 2005 - nature.com
Hypertension is a complex multifactorial disorder with genetic, environmental and
demographic factors contributing to its prevalence. The genetic element contribution to …

Genetics of hypertension: discoveries from the bench to human populations

N Franceschini, TH Le - American Journal of Physiology …, 2014 - journals.physiology.org
Hypertension is a complex trait that is influenced by both heritable and environmental
factors. The search for genes accounting for the susceptibility to hypertension has driven …

Functional genomics in hypertension

MW McBride, D Graham, C Delles… - Current opinion in …, 2006 - journals.lww.com
The genetic basis of hypertension is complex, and the examination of the functional
consequences of genetic variants in particular is still challenging. A number of tools are now …

Sodium excretion as a modulator of genetic associations with cardiovascular phenotypes in the European Project on Genes in Hypertension

T Kuznetsova, JA Staessen, E Brand… - Journal of …, 2006 - journals.lww.com
Hypertension is a chronic age-related disorder, affecting nearly 20% of all adult Europeans.
This disease entails debilitating cardiovascular complications and is the leading cause for …

Hypertension and genes: perspectives from this journal

J Chackathayil, JV Patel, B Cheung - Journal of human hypertension, 2007 - nature.com
Hypertension is a complex multifactorial disorder with many genetic, environmental and
demographic factors contributing to this disorder. 1 As recently reviewed by Tanira and …

Contemporary approaches to genetic influences on hypertension

MM Fung, K Zhang, L Zhang, F Rao… - Current opinion in …, 2011 - journals.lww.com
Hypertension appears to have many genetic contributions from each regulatory area
ranging from DNA to RNA to protein to postprotein to interactive influences of the …

[HTML][HTML] Genetic basis of hypertension for the development of tailored medicine

T Katsuya, R Morishita, H Rakugi, T Ogihrara - Hypertension Research, 2009 - nature.com
Similar to a tsunami wave, a new surge of genome-wide association studies in common
complex diseases has succeeded in identifying the causative genetic risk factors of …