Cancer stem cells (CSCs) are a sub-population of cells within cancer tissues with tumor
initiation, drug resistance and metastasis properties. CSCs also have been considered as …

Cancer stem cells (CSC) have raised great excitement during the last decade and are
promising targets for an efficient treatment of tumors without relapses and metastases …

Traditional therapies against cancer, chemo-and radiotherapy, have multiple limitations that
lead to treatment failure and cancer recurrence. These limitations are related to systemic …

Background Non-adherent or ultra-low attachment three-dimensional (3D) culture, also
called sphere formation assay, has been widely used to assess the malignant phenotype …

Simple Summary Circulating cancer cells—and in particular their very rare subpopulation,
circulating cancer stem cells (cCSCs)—are responsible for recurrence and metastasis. In …

Background Cancer stem cells (CSCs) play an important role in tumor initiation, progression,
and metastasis and are responsible for high therapeutic failure rates. Identification and …

Recent advances in research on cancer have led to understand the pathogenesis of cancer
and development of new anticancer drugs. Despite of these advancements, many tumors …

Cancer cells, stem cells and cancer stem cells have for a long time played a significant role
in the biomedical sciences. Though cancer therapy is more effective than it was a few years …

Nowadays, cancer has been a frequent disease, and the first or second most common cause
of death worldwide. Despite a better understanding of the biology of cancer cells, the …

Cancer stem cells (CSCs) are a small subpopulation of cells within tumors with capabilities
of self-renewal, differentiation, and tumorigenicity. Successful cancer treatment would need …