The non-coding RNA interactome in joint health and disease

SA Ali, MJ Peffers, MJ Ormseth, I Jurisica… - Nature Reviews …, 2021 - nature.com
Non-coding RNAs have distinct regulatory roles in the pathogenesis of joint diseases
including osteoarthritis (OA) and rheumatoid arthritis (RA). As the amount of high-throughput …

The emerging role of non-coding RNAs in osteoarthritis

S Ghafouri-Fard, C Poulet, M Malaise, A Abak… - Frontiers in …, 2021 - frontiersin.org
Osteoarthritis (OS) is the most frequent degenerative condition in the joints, disabling many
adults. Several abnormalities in the articular cartilage, subchondral bone, synovial tissue …

[PDF][PDF] Long noncoding RNAs in the regulation of inflammatory pathways in rheumatoid arthritis and osteoarthritis

MJ Pearson, SW Jones - Arthritis & rheumatology, 2016 - Wiley Online Library
It was initially envisaged that upon completion of the Human Genome Project, our
understanding of human disease would lead to the development of abundant new targeted …

Non-coding RNAs in rheumatoid arthritis: from bench to bedside

J Wang, S Yan, J Yang, H Lu, D Xu… - Frontiers in immunology, 2020 - frontiersin.org
Rheumatoid arthritis is a common systemic and autoimmune disease characterized by
symmetrical and inflammatory destruction of distal joints. Its primary pathological characters …

LncRNAs in osteoarthritis

HM Okuyan, MA Begen - Clinica Chimica Acta, 2022 - Elsevier
Osteoarthritis (OA) is a progressive joint disease that affects millions of older adults around
the world. With increasing rates of incidence and prevalence worldwide, OA has become an …

MicroRNAs in synovial pathology associated with osteoarthritis

G Tavallaee, JS Rockel, S Lively, M Kapoor - Frontiers in medicine, 2020 - frontiersin.org
Osteoarthritis (OA) is the most common type of arthritis, a disease that affects the entire joint.
The relative involvement of each tissue, and their interactions, add to the complexity of OA …

Noncoding RNAs: new regulatory code in chondrocyte apoptosis and autophagy

S Jiang, Y Liu, B Xu, Y Zhang… - Wiley Interdisciplinary …, 2020 - Wiley Online Library
Osteoarthritis (OA) is a bone and joint disease characterized by progressive cartilage
degradation. In the face of global trends of population aging, OA is expected to become the …

Macro view of microRNA function in osteoarthritis

S Miyaki, H Asahara - Nature Reviews Rheumatology, 2012 - nature.com
Osteoarthritis (OA), the most common musculoskeletal disorder, is complex, multifaceted,
and characterized by degradation of articular cartilage and alterations in other joint tissues …

[HTML][HTML] Emerging roles of long noncoding RNA in chondrogenesis, osteogenesis, and osteoarthritis

H Sun, G Peng, X Ning, J Wang, H Yang… - American journal of …, 2019 - ncbi.nlm.nih.gov
Osteoarthritis (OA) is the most prevalent age-related debilitating joint disease, and is
characterized primarily by articular cartilage degradation and subchondral bone lesions. It is …

[PDF][PDF] Long intergenic noncoding RNAs mediate the human chondrocyte inflammatory response and are differentially expressed in osteoarthritis cartilage

MJ Pearson, AM Philp, JA Heward… - Arthritis & …, 2016 - Wiley Online Library
Objective To identify long noncoding RNAs (lncRNAs), including long intergenic noncoding
RNAs (lincRNAs), antisense RNAs, and pseudogenes, associated with the inflammatory …