Since the exploration of sequencing began in 2005, third and next-generation sequencing
(TGS and NGS) technologies have fundamentally changed metagenomics research. These …

Shotgun metagenomic sequencing is a common approach for studying the taxonomic
diversity and metabolic potential of complex microbial communities. Current methods …

Rapid and sensitive diagnostic strategies are necessary for patient care and public health.
Most of the current conventional microbiological assays detect only a restricted panel of …

A trend towards the abandonment of obtaining pure culture isolates in frontline laboratories
is at a crossroads with the ability of public health agencies to perform their basic mandate of …

Introduction Metagenomic next-generation sequencing (mNGS) assay for detecting
infectious agents is now in the stage of being translated into clinical practice. With no …

The development of next generation sequencing (NGS) techniques has enabled
researchers to study and understand the world of microorganisms from broader and deeper …

The study of microbial communities has undergone significant advancements, starting from
the initial use of 16S rRNA sequencing to the adoption of shotgun metagenomics. However …

Over the last two decades, sequencing tools have evolved from laborious time-consuming
methodologies to real-time detection and deciphering of genomic DNA. Genome …

Microorganisms are the major part of earth's biological diversity. Due to most of the microbes
being nonculturable, it is necessary to use culture independent techniques to study the …

The application of sequencing technology is shifting from research to clinical laboratories
owing to rapid technological developments and substantially reduced costs. However …