The identification of variable-length coevolutionary patterns for predicting HIV-1 protease cleavage sites
Z Li, L Hu - 2020 IEEE international conference on systems …, 2020 - ieeexplore.ieee.org
The substrate specificity of human immunodeficiency virus 1 (HIV-1) plays an essential role
in designing HIV-1 inhibitors for therapy purpose. Hence, to predict the existence of …
in designing HIV-1 inhibitors for therapy purpose. Hence, to predict the existence of …
[HTML][HTML] Effectively predicting HIV-1 protease cleavage sites by using an ensemble learning approach
Background The site information of substrates that can be cleaved by human
immunodeficiency virus 1 proteases (HIV-1 PRs) is of great significance for designing …
immunodeficiency virus 1 proteases (HIV-1 PRs) is of great significance for designing …
Performance Analysis of Deep CNN Assisted Optimized HIV-I Protease Cleavage Site Prediction with Hybridized Technique
In recent years, human immunodeficiency virus infection and acquired immune deficiency
syndrome (HIV/AIDS) has emerged as a global health issue. The disease is caused by a …
syndrome (HIV/AIDS) has emerged as a global health issue. The disease is caused by a …
Incorporating the coevolving information of substrates in predicting HIV-1 protease cleavage sites
Human immunodeficiency virus 1 (HIV-1) protease (PR) plays a crucial role in the
maturation of the virus. The study of substrate specificity of HIV-1 PR as a new endeavor …
maturation of the virus. The study of substrate specificity of HIV-1 PR as a new endeavor …
Mining Classification Rules for HIV-1 Protease Cleavage Sites Using Simplified Swarm Optimization
A Yeh, WC Yeh - Proceedings of the 2019 International Conference on …, 2019 - dl.acm.org
HIV-1 protease is a crucial enzyme in the HIV life cycle and serves to cleave the polyprotein
that is involved in the formation of mature viruses. Due to its sensitivity and important …
that is involved in the formation of mature viruses. Due to its sensitivity and important …
Evolutionary based ensemble framework for realizing transfer learning in HIV-1 Protease cleavage sites prediction
The role of human immunodeficiency virus (HIV) protease in viral maturation is
indispensable as the drug therapy primarily targets the HIV protease for the treatment of …
indispensable as the drug therapy primarily targets the HIV protease for the treatment of …
[HTML][HTML] Prediction of HIV-1 protease cleavage site using a combination of sequence, structural, and physicochemical features
O Singh, ECY Su - BMC bioinformatics, 2016 - Springer
Background The human immunodeficiency virus type 1 (HIV-1) aspartic protease is an
important enzyme owing to its imperative part in viral development and a causative agent of …
important enzyme owing to its imperative part in viral development and a causative agent of …
Comparison among feature encoding techniques for HIV-1 protease cleavage specificity
HIV-1 protease which is responsible for the generation of infectious viral particles by
cleaving the virus polypeptides, play an indispensable role in the life cycle of HIV-1 …
cleaving the virus polypeptides, play an indispensable role in the life cycle of HIV-1 …
[HTML][HTML] A new approach for HIV-1 protease cleavage site prediction combined with feature selection
Y Yuan, H Liu, G Qiu - Journal of Biomedical Science and Engineering, 2013 - scirp.org
Acquired immunodeficiency syndrome (AIDS) is a fatal disease which highly threatens the
health of human being. Human immunodeficiency virus (HIV) is the pathogeny for this …
health of human being. Human immunodeficiency virus (HIV) is the pathogeny for this …
Integrating Multi-view Feature Extraction and Fuzzy Rank-Based Ensemble for Accurate HIV-1 Protease Cleavage Site Prediction
Acquired immunodeficiency syndrome (AIDS) continues to be a significant cause of
mortality, disability, and economic repercussions, especially in underdeveloped countries …
mortality, disability, and economic repercussions, especially in underdeveloped countries …