Background Africa is the origin of modern humans within the past 300 thousand years. To
infer the complex demographic history of African populations and adaptation to diverse …

In the last three decades, genetic studies have played an increasingly important role in
exploring human history. They have helped to conclusively establish that anatomically …

Abstract The southern African indigenous Khoe-San populations harbor the most divergent
lineages of all living peoples. Exploring their genomes is key to understanding deep human …

The geostrategic location of North Africa as a crossroad between three continents and as a
stepping-stone outside Africa has evoked anthropological and genetic interest in this region …

Genetic variation and susceptibility to disease are shaped by human demographic history
and adaptation. We can now study the genomes of extant Africans and uncover traces of …

Northeast Africa has a long history of human habitation, with fossil-finds from the earliest
anatomically modern humans, and housing ancient civilizations. The region is also the gate …

Background Population demography and gene flow among African groups, as well as the
putative archaic introgression of ancient hominins, have been poorly explored at the …

Southern Africa is consistently placed as a potential region for the evolution of Homo
sapiens. We present genome sequences, up to 13x coverage, from seven ancient …

We assembled genome-wide data from 16 prehistoric Africans. We show that the anciently
divergent lineage that comprises the primary ancestry of the southern African San had a …

Genetic and archaeological studies have established a sub-Saharan African origin for
anatomically modern humans with subsequent migrations out of Africa. Using the largest …