Role of dietary supplements and probiotics in modulating microbiota and bone health: the gut-bone axis

A de Sire, R de Sire, C Curci, F Castiglione, W Wahli - Cells, 2022 - mdpi.com
Osteoporosis is characterized by an alteration of bone microstructure with a decreased bone
mineral density, leading to the incidence of fragility fractures. Around 200 million people are …

The human gut microbiota: a key mediator of osteoporosis and osteogenesis

KD Seely, CA Kotelko, H Douglas, B Bealer… - International journal of …, 2021 - mdpi.com
An expanding body of research asserts that the gut microbiota has a role in bone
metabolism and the pathogenesis of osteoporosis. This review considers the human gut …

Gut microbiota and bone diseases: a growing partnership

Y Chen, X Wang, C Zhang, Z Liu, C Li… - Frontiers in Microbiology, 2022 - frontiersin.org
Gut microbiota is key to human health and disease. Convincing studies have demonstrated
that dysbiosis in the commensal gut microbiota is associated with intestinal and extra …

Healthy gut, healthy bones: targeting the gut microbiome to promote bone health

OD Cooney, PR Nagareddy, AJ Murphy… - Frontiers in …, 2021 - frontiersin.org
Over the past decade, the use of probiotics to modify the gut microbiome has become a
public spotlight in reducing the severity of a number of chronic diseases such as …

Gut microbiota-bone axis

CR Villa, WE Ward, EM Comelli - Critical reviews in food science …, 2017 - Taylor & Francis
The gut microbiota (GM) is an important regulator of body homeostasis, including intestinal
and extra-intestinal effects. This review focuses on the GM-bone axis, which we define as …

New advances in improving bone health based on specific gut microbiota

Q Yan, L Cai, W Guo - Frontiers in cellular and infection microbiology, 2022 - frontiersin.org
The gut microbiota has been shown to play an important role in the pathogenesis of various
diseases, including metabolic diseases, cardiovascular diseases, and cancer. Recent …

The microbiota-gut-bone axis and bone health

Y Tu, R Yang, X Xu, X Zhou - Journal of leukocyte biology, 2021 - academic.oup.com
The gastrointestinal tract is colonized by trillions of microorganisms, consisting of bacteria,
fungi, and viruses, known as the “second gene pool” of the human body. In recent years, the …

Intestinal microbiota: a potential target for the treatment of postmenopausal osteoporosis

X Xu, X Jia, L Mo, C Liu, L Zheng, Q Yuan, X Zhou - Bone research, 2017 - nature.com
Postmenopausal osteoporosis (PMO) is a prevalent metabolic bone disease characterized
by bone loss and structural destruction, which increases the risk of fracture in …

Modulation of bone remodeling by the gut microbiota: a new therapy for osteoporosis

Z Lyu, Y Hu, Y Guo, D Liu - Bone research, 2023 - nature.com
The gut microbiota (GM) plays a crucial role in maintaining the overall health and well-being
of the host. Recent studies have demonstrated that the GM may significantly influence bone …

The potential of probiotics as a therapy for osteoporosis

FL Collins, ND Rios-Arce, JD Schepper… - Microbiology …, 2017 - Am Soc Microbiol
Osteoporosis, characterized by low bone mass and micro-architectural deterioration of bone
tissue with increased risk of fracture, can be categorized into two forms: primary and …