Importance Cardiovascular disease (CVD) is the leading cause of mortality in the US,
accounting for more than 1 in 4 deaths. Each year, an estimated 605 000 people in the US …

Background: Coronary heart disease and cerebrovascular disease are leading causes of
death in the United States. In 2002, the US Preventive Services Task Force (USPSTF) …

Description: Update of the 2002 US Preventive Services Task Force (USPSTF)
recommendation about the use of aspirin for the prevention of coronary heart disease …

Importance Low-dose aspirin is used for primary cardiovascular disease prevention and
may have benefits for colorectal cancer prevention. Objective To review the benefits and …

Background: Evidence indicates that aspirin is effective for the primary prevention of
cardiovascular disease (CVD) and colorectal cancer (CRC) but also increases the risk for …

Background: The use of aspirin to prevent cardiovascular disease events in patients without
a history of cardiovascular disease is controversial. Purpose: To examine the benefits and …

Background: Cardiovascular disease (CVD) is the leading cause of death in the United
States. Purpose: To update a systematic review about the benefits of aspirin for the primary …

Importance Clinical decision making regarding the appropriate use of aspirin for the primary
prevention of atherosclerotic cardiovascular disease (ASCVD) events is complex, and …

ContextMore than 50 million US adults take aspirin regularly for long-term prevention of
cardiovascular disease, typically either 81 mg/d or 325 mg/d. Controversy remains regarding …

Antiplatelet therapy, most notably aspirin, has been well documented to reduce risks of
subsequent cardiovascular disease (CVD) in secondary prevention, acute myocardial …