Neurons in the hippocampus exhibit a striking selectivity for specific combinations of sensory
features, forming representations that are thought to subserve episodic memory. Even …

The hippocampus is critical for producing stable representations of familiar spaces. How
these representations arise is poorly understood, largely because changes to hippocampal …

The acquisition of new memories for places and events requires synaptic plasticity in the
hippocampus, and plasticity depends on temporal coordination among neurons. Spatial …

Animals display an innate preference for novelty, spending more time exploring both novel
objects and familiar objects in novel locations. This increase in exploration is thought to …

When exploring new environments animals form spatial memories that are updated with
experience and retrieved upon re-exposure to the same environment. The hippocampus is …

Learning critically depends on the ability to rapidly form and store non-overlapping
representations of the external world. In line with their postulated role in episodic memory …

Hippocampal cells are central to spatial and predictive representations, and experience
replays by place cells are crucial for learning and memory. Nonetheless, how hippocampal …

The hippocampus is thought to have a critical role in episodic memory by incorporating the
sensory input of an experience onto a spatial framework embodied by place cells. Although …

Memory models often emphasize the need to encode novel patterns of neural activity
imposed by sensory drive. Prior learning and innate architecture likely restrict neural …

Learning requires neural adaptations thought to be mediated by activity-dependent synaptic
plasticity. A relatively non-standard form of synaptic plasticity driven by dendritic calcium …