Vascular endothelial growth factor (VEGF) represents a growth factor with important pro-
angiogenic activity, having a mitogenic and an anti-apoptotic effect on endothelial cells …

Vasculogenesis and angiogenesis are the mechanisms responsible for the development of
the blood vessels. Angiogenesis refers to the formation of capillaries from pre-existing …

The VEGF (vascular endothelial growth factor) family and its receptors are essential
regulators of angiogenesis and vascular permeability. Currently, the VEGF family consists of …

Angiogenesis is a process of development and of growth of new capillary blood vessels from
pre-existing vessels. When pathological, it contributes to the development of numerous …

The dependence of tumor growth on the development of a neovasculature is well-
established [1]. After a tumor grows beyond 100 mm to 200 mm in size, diffusion alone is no …

Vascular endothelial growth factor (VEGF) has proven to be the most critical angiogenic
factor identified to date; its discovery has transformed the field of angiogenesis research …

The VEGF/VPF (vascular endothelial growth factor/vascular permeability factor) ligands and
receptors are crucial regulators of vasculogenesis, angiogenesis, lymphangiogenesis and …

Vascular endothelial growth factor (VEGF) is a homodimeric glycoprotein with a molecular
weight of approximately 45 kDa. It is the key mediator of angiogenesis (the formation of new …

The vascular endothelial growth factor (VEGF)/VEGF receptor system plays a central
regulatory role in physiological and pathological angiogenesis. During embryogenesis, the …

Vascular endothelial growth factor (VEGF)-A, a major regulator for angiogenesis, binds and
activates two tyrosine kinase receptors, VEGFR1 (Flt-1) and VEGFR2 (KDR/Flk-1). These …