Chronic kidney diseases (CKDs) are currently classified according to their clinical features,
associated comorbidities and pattern of injury on biopsy. Even within a given classification …

Abstract Chronic Kidney Disease (CKD) represents a slowly progressive disorder that is
typically silent until late stages, but early intervention can significantly delay its progression …

Chronic kidney disease (CKD) has diverse phenotypic manifestations including structural
(such as fibrosis) and functional (such as glomerular filtration rate and albuminuria) …

Kidney diseases manifest in progressive loss of renal function, which ultimately leads to
complete kidney failure. The mechanisms underlying the origins and progression of kidney …

The quest for the ideal therapeutic target in chronic kidney disease (CKD) has been riddled
with many obstacles stemming from the molecular complexity of the disease and its co …

Chronic kidney disease (CKD) and acute kidney injury (AKI) are common, heterogeneous,
and morbid diseases. Mechanistic characterization of CKD and AKI in patients may facilitate …

In this review of the application of proteomics and metabolomics to kidney disease research,
we review key concepts, highlight illustrative examples, and outline future directions. The …

Background In spite of its invasive nature and risks, kidney biopsy is currently required for
precise diagnosis of many chronic kidney diseases (CKDs). Here, we explored the …

The advent of next-generation sequencing technologies has enabled genetic nephrology
research to move beyond single gene analysis to the simultaneous investigation of …

The current unidimensional paradigm of kidney disease detection is incompatible with the
complexity and heterogeneity of renal pathology. The diagnosis of kidney disease has …