Management of hypertension in CKD: beyond the guidelines

E Judd, DA Calhoun - Advances in chronic kidney disease, 2015 - Elsevier
Hypertension (HTN) and CKD are closely associated with an intermingled cause and effect
relationship. Blood pressure (BP) typically rises with declines in kidney function, and …

Bedtime dosing of antihypertensive medications reduces cardiovascular risk in CKD

RC Hermida, DE Ayala, A Mojon… - Journal of the American …, 2011 - journals.lww.com
Time of ingestion of hypertension medications can affect circadian patterns of BP, but
whether this translates into an effect on clinical outcomes is unknown. Here, in an open …

Hypertension in CKD: core curriculum 2019

E Ku, BJ Lee, J Wei, MR Weir - American Journal of Kidney Diseases, 2019 - Elsevier
Hypertension and chronic kidney disease (CKD) are closely interlinked pathophysiologic
states, such that sustained hypertension can lead to worsening kidney function and …

Changing the timing of antihypertensive therapy to reduce nocturnal blood pressure in CKD: an 8-week uncontrolled trial

R Minutolo, FB Gabbai, S Borrelli, R Scigliano… - American journal of …, 2007 - Elsevier
BACKGROUND: Nondipping status is associated with greater cardiovascular morbidity and
mortality and faster progression of chronic kidney disease (CKD). We examined whether …

Chronotherapy improves blood pressure control and reduces vascular risk in CKD

RC Hermida, DE Ayala, MH Smolensky… - Nature Reviews …, 2013 - nature.com
In patients with chronic kidney disease (CKD), the prevalence of increased blood pressure
during sleep and blunted sleep-time-relative blood pressure decline (a nondipper pattern) is …

Hypertension in chronic kidney disease

SM Hamrahian, B Falkner - Hypertension: from basic research to clinical …, 2017 - Springer
Hypertension, a global public health problem, is currently the leading factor in the global
burden of disease. It is the major modifiable risk factor for heart disease, stroke and kidney …

Administration-time-dependent effects of hypertension treatment on ambulatory blood pressure in patients with chronic kidney disease

JJ Crespo, L Piñeiro, A Otero, C Castiñeira… - Chronobiology …, 2013 - Taylor & Francis
Many published prospective trials have reported clinically meaningful morning-evening,
treatment-time differences in the blood pressure (BP)-lowering efficacy, duration of action …

Hypertension in chronic kidney disease: navigating the evidence

FM Tedla, A Brar, R Browne… - International journal of …, 2011 - Wiley Online Library
Hypertension is both an important cause and consequence of chronic kidney disease.
Evidence from numerous clinical trials has demonstrated the benefit of blood pressure …

Administration–time-dependent effects of blood pressure-lowering medications: basis for the chronotherapy of hypertension

MH Smolensky, RC Hermida, DE Ayala… - Blood pressure …, 2010 - journals.lww.com
There is growing interest on how to best tailor blood pressure (BP)-lowering medications
according to the circadian (24 h) BP pattern of individual patients, that is, chronotherapy …

A trial of 2 strategies to reduce nocturnal blood pressure in blacks with chronic kidney disease

M Rahman, T Greene, RA Phillips, LY Agodoa… - …, 2013 - Am Heart Assoc
The objective of our study was to determine the effects of 2 antihypertensive drug dose
schedules (PM dose and add-on dose) on nocturnal blood pressure (BP) in comparison with …