Real-life use of high-dose anakinra in patients with COVID-19 treated with remdesivir

R Monardo, A Mastrangelo, L Galli, A Tomelleri… - Future …, 2024 - Future Medicine
Aim: Aim of this study was to evaluate the effect of anakinra (ANK) addition to remdesivir
(RDV) on all-cause 28-day mortality in patients hospitalized with COVID-19. Patients & …

[HTML][HTML] Clinical Effectiveness and Adverse Events of Adjunctive Remdesivir Administration Vs Standard of Care in Adults with Severe and Critical Covid-19

DD Viray, TP Cajulao, B Demot, S Bartolo… - International Journal of …, 2023 - Elsevier
Intro The unavailability of specific treatment for COVID-19 prompted the empirical use of
remdesivir, a viral RNA polymerase inhibitor. Since evidences present conflicting results …

[HTML][HTML] Evaluation of safety and effectiveness of remdesivir in treating COVID-19 patients after emergency use authorization study

E Burhan, E Syahruddin, F Isbaniah… - Frontiers in …, 2023 - frontiersin.org
Background: This study aimed to determine the real-world safety and effectiveness of
remdesivir in hospitalized adult COVID-19 patients with moderate-to-critical disease in …

[HTML][HTML] Efficacy of remdesivir-containing therapy in hospitalized COVID-19 patients: a prospective clinical experience

A Russo, E Binetti, C Borrazzo, EG Cacciola… - Journal of clinical …, 2021 - mdpi.com
Objectives: Remdesivir is currently approved for the treatment of COVID-19. The
recommendation for using remdesivir in patients with COVID-19 was based on the in vitro …

Outcome of Remdesivir on Mortality in Patients with COVID-19 Pneumonia

J Yayan, K Rasche, W Windisch, KJ Franke - 2023 - researchsquare.com
Methods In this single-center, retrospective study, we evaluated data of patients hospitalized
for COVID-19 pneumonia at the Lüdenscheid Clinic in Germany from January 1, 2020, to …

Safety and efficacy of remdesivir for the treatment of COVID-19: a systematic review and meta-analysis

MT Gholamhoseini… - … of Pharmacy & …, 2021 - journals.library.ualberta.ca
Purpose: To evaluate the safety and efficacy of remdesivir in adult patients with COVID-19.
Methods: PubMed, Embase, Scopus, Web of Science, Cochrane Library, ClinicalTrials. gov …

[HTML][HTML] Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial

Y Wang, D Zhang, G Du, R Du, J Zhao, Y Jin, S Fu… - The lancet, 2020 - thelancet.com
Background No specific antiviral drug has been proven effective for treatment of patients
with severe coronavirus disease 2019 (COVID-19). Remdesivir (GS-5734), a nucleoside …

[HTML][HTML] Remdesivir for 5 or 10 days in patients with severe Covid-19

JD Goldman, DCB Lye, DS Hui, KM Marks… - … England Journal of …, 2020 - Mass Medical Soc
Background Remdesivir is an RNA polymerase inhibitor with potent antiviral activity in vitro
and efficacy in animal models of coronavirus disease 2019 (Covid-19). Methods We …

Remdesivir for the treatment of COVID-19 disease: A retrospective comparative study of patients treated with and without Remdesivir

S Madan, A Patel, K Sharan, S Ghosh, V Venugopal… - medRxiv, 2021 - medrxiv.org
Background Remdesivir (RDV) in coronavirus disease 2019 (COVID-19) has been found to
be beneficial in patients with severe disease; however, its role in mild-moderate disease and …

Clinical outcomes of COVID‐19 treated with remdesivir across the continuum of care

CG Rivera, S Chesdachai, EW Draper… - Influenza and Other …, 2023 - Wiley Online Library
Introduction During the early phase of the coronavirus disease 2019 (COVID‐19), remdesivir
was only approved for hospitalized patients. Our institution developed hospital‐based …