Although the global pandemic caused by the novel severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) is still ongoing, there are currently no specific and highly …

SARS-CoV-2, a novel beta-coronavirus (CoV), causes the coronavirus disease 2019
(COVID-19) pandemic, which manifests with a wide clinical spectrum ranging from …

COVID-19, the infectious disease caused by SARS-CoV-2, has spread on a pandemic scale.
The viral infection can evolve asymptomatically or can generate severe symptoms …

The emergence of novel variants of SARS-CoV-2 and their abilities to evade the immune
response elicited through presently available vaccination makes it essential to recognize the …

The SARS-CoV-2 pandemic has resulted in millions of infections, yet the role of host
immune responses in early COVID-19 pathogenesis remains unclear. By investigating 17 …

SARS-CoV-2 causes COVID-19, an infectious disease with symptoms ranging from a mild
cold to severe pneumonia, inflammation, and even death. Although strong inflammatory …

The contribution of CD4+ T cells to protective or pathogenic immune responses to SARS-
CoV-2 infection remains unknown. Here, we present single-cell transcriptomic analysis of> …

Virus-specific T cells play essential roles in protection against multiple virus infections,
including SARS-CoV and MERS-CoV. While SARS-CoV-2–specific T cells have been …

As an important part of adaptive immunity, T cells are indispensable in the defense against
pathogens including viruses. SARS-CoV-2 is a new human coronavirus that occurred at the …

The molecular properties of CD8+ T cells that respond to SARS-CoV-2 infection are not fully
known. Here, we report on the single-cell transcriptomes of> 80,000 virus-reactive CD8+ T …