Working memory, a fundamental cognitive function that is highly dependent on the integrity
of the prefrontal cortex, is known to show age-related decline across the typical healthy adult …

Working memory is an executive memory process that allows transitional information to be
held and manipulated temporarily in memory stores before being forgotten or encoded into …

Individuals differ in how they perceive, remember, and think. There is evidence for the
existence of distinct subgroups that differ in cognitive performance within the older …

Working memory subsumes the capability to memorize, retrieve and utilize information for a
limited period of time which is essential to many human behaviours. Moreover, impairments …

Positron emission tomography (PET) and functional magnetic resonance imaging (fMRI)
studies have revealed age-related under-activation, where older adults show less regional …

The n-back task is a classical paradigm for functional neuroimaging studies of working
memory (WM). The frontal and parietal cortical regions are known to be activated during the …

Working memory (WM) shows pronounced age-related decline. Functional magnetic
resonance imaging (fMRI) studies have revealed age differences in task-related brain …

One of the most popular experimental paradigms for functional neuroimaging studies of
working memory has been the n‐back task, in which subjects are asked to monitor the …

Although recent neuroimaging studies suggest that prefrontal cortex (PFC) is involved in
working memory (WM), the relationship between PFC activity and memory load has not yet …

Lesion studies in monkeys have provided evidence that lateral prefrontal cortex is necessary
for working memory, the cognitive processes involved in the temporary maintenance and …