Effect of axial ligand length on biological and anticancer properties of axially disubstituted silicon phthalocyanines

HY Yenilmez, N Farajzadeh… - Chemistry & …, 2023 - Wiley Online Library
In this study, three new axially disubstituted silicon phthalocyanines (SiPc1–3) and their
quaternized phthalocyanine derivatives (QSiPc1–3) were prepared and characterized. The …

Silicon Phthalocyanines as Anti‐infectious, Antioxidant, and Anticancer Agents

HY Yenilmez, N Farajzadeh, G Tollu… - …, 2023 - Wiley Online Library
This study reports the synthesis of three silicon phthalocyanines (SiPc1–3) bearing 2‐
dimethylaminoethoxy, 2‐[2‐(dimethylamino) ethoxy] ethoxy, or 2‐{2‐[2‐(dimethylamino) …

Anticancer and biological properties of new axially disubstituted silicon phthalocyanines

N Farajzadeh, NG Kuşçulu, HY Yenilmez… - Dalton …, 2022 - pubs.rsc.org
This study reports the synthesis of three novel axially disubstituted silicon phthalocyanines
(1–3-Si) and their quaternized phthalocyanines (1–3-QSi). The resulting compounds were …

Anticancer activity of novel silicon phthalocyanines against the colorectal adenocarcinoma cell line (DLD-1)

N Farajzadeh, NG Kuşçulu, HY Yenilmez… - New Journal of …, 2022 - pubs.rsc.org
In this study, the DNA cleavage activities of a series of new silicon phthalocyanines were
studied to measure their potential for cancer treatment. For this purpose, 2-(2, 4, 6-tris …

Design, synthesis and biological evaluation of water soluble and non-aggregated silicon phthalocyanines, naphthalocyanines against A549, SNU-398, SK-MEL128 …

T Keleş, B Barut, A Özel, Z Biyiklioglu - Bioorganic Chemistry, 2021 - Elsevier
Cancer has become an important public problem in worldwide since cancer incidence and
mortality are growing rapidly. In this study, water soluble and non-aggregated silicon (IV) …

Novel axially symmetric and unsymmetric silicon (iv) phthalocyanines having anti-inflammatory groups: synthesis, characterization and their biological properties

GG Çelik, S Gonca, B Şahin, S Özdemir, D Atilla… - Dalton …, 2022 - pubs.rsc.org
New asymmetric Si (IV) Pc (1), monomeloxicammonotriethyleneglycolmon…
(phthalocyaninano) silicone, axially ligated with meloxicam as a non-steroidal anti …

Synthesis of water soluble silicon phthacyanine, naphthalocyanine bearing pyridine groups and investigation of their DNA interaction, topoisomerase inhibition …

T Keleş, B Barut, A Özel, Z Biyiklioglu - Dyes and Pigments, 2019 - Elsevier
Abstract In this work, axially [3, 5-bis (3-pyridin-4-ylpropoxy) phenyl] methoxy groups
substituted silicon (IV) phthalocyanine 2, napthalocyanine 3 and their water soluble …

Highly water soluble axial disubstituted silicon (IV) phthalocyanine, naphthalocyanine: Synthesis, DNA interaction and anticancer effects against human lung (A549) …

H Baş, Z Biyiklioglu, B Barut, CÖ Yalçın… - Inorganic Chemistry …, 2023 - Elsevier
Photodynamic therapy (PDT) is a growing clinical approach used to treat some life-
threatening diseases, particularly cancer. PDT makes it possible to inhibit the growth of …

The phenoxy-bearing naphthalimide substituted phthalocyanines: Photophysicochemical and biological properties

T Küçük, K Harmandar, MS Yalçın, ŞŞ Ün… - Polyhedron, 2024 - Elsevier
Abstract New Si (IV) phthalocyanine (Pc)(1) derivative including axially phenoxy bearing
naphthalimide and peripheraly t-butyl groups was synthesized and photophysicochemical …

Non-aggregated axially disubstituted silicon phthalocyanines: Synthesis, DNA cleavage and in vitro cytotoxic/phototoxic anticancer activities against SH-SY5Y cell line

B Barut, Z Biyiklioglu, CÖ Yalçın, M Abudayyak - Dyes and Pigments, 2020 - Elsevier
Abstract In this paper, axially {6-[3-(dimethylamino) phenoxy] hexyl} oxy and {6-[3-
(diethylamino) phenoxy] hexyl} oxy groups substituted silicon phthalocyanines were …