Glioblastoma multiforme (GBM) is a WHO grade IV glioma and the most common malignant,
primary brain tumor with a 5-year survival of 7.2%. Its highly infiltrative nature, genetic …

Glioblastoma multiforme (GBM) is a grade IV brain tumor characterized by a heterogeneous
population of cells that are highly infiltrative, angiogenic and resistant to chemotherapy. The …

Malignant gliomas such as glioblastoma multiforme (GBM) present some of the greatest
challenges in the management of cancer patients worldwide, despite notable recent …

Glioblastoma is the commonest primary brain tumor, as well as the deadliest. Malignant
gliomas such as glioblastoma multiforme (GBM) present some of the greatest challenges in …

Introduction The increasingly detailed genetic characterization of glioblastoma (GBM) has
failed to translate into meaningful breakthroughs in treatment. This is likely to be attributed to …

Glioblastoma multiforme (GBM) is the most common and fatal primary brain tumor, is highly
resistant to conventional radiation and chemotherapy, and is not amenable to effective …

Glioblastoma multiforme (GBM) is the most common primary brain tumour, and the most
aggressive in nature. The prognosis for patients with GBM remains poor, with a median …

Glioblastoma (GBM) is the most common primary central nervous system tumor in adults. It is
a highly invasive disease, making it difficult to achieve a complete surgical resection …

Heterogeneity is a hallmark of tumors and has a crucial role in the outcome of the
malignancy, because it not only confounds diagnosis, but also challenges the design of …

Abstract Each year, about 5–6 cases out of 100,000 people are diagnosed with primary
malignant brain tumors, of which about 80% are malignant gliomas (MGs). Glioblastoma …