MicroRNA‑223 overexpression suppresses protein kinase C ε expression in human leukemia stem cell‑like KG‑1a cells

M Osiriphan, C Insukhin… - Molecular and …, 2024 - spandidos-publications.com
Abstract MicroRNA‑223 (miR‑223) is dysregulated in various cancer types, including acute
myeloid leukemia (AML). Despite this, there has been a lack of studies exploring the role of …

[HTML][HTML] MicroRNA 217 inhibits cell proliferation and enhances chemosensitivity to doxorubicin in acute myeloid leukemia by targeting KRAS

Y Xiao, T Deng, C Su, Z Shang - Oncology letters, 2017 - spandidos-publications.com
Acute myeloid leukemia (AML) is a heterogeneous malignant disorder derived from the
myeloid hematopoietic cells that accounts for~ 80% of all adult acute leukemia. Numerous …

[HTML][HTML] An evolutionarily conserved mechanism for microRNA-223 expression revealed by microRNA gene profiling

T Fukao, Y Fukuda, K Kiga, J Sharif, K Hino, Y Enomoto… - Cell, 2007 - cell.com
Many microRNAs (miRNAs) are evolutionarily conserved and have intriguing expression
patterns. Tissue and/or time-specific expressions of some miRNAs are presumably …

miR-223 decreases cell proliferation and enhances cell apoptosis in acute myeloid leukemia via targeting FBXW7

Y Xiao, C Su, T Deng - Oncology letters, 2016 - spandidos-publications.com
The expression of microRNA-223 (miR-233) has been investigated in various types of
cancer. However, to the best of our knowledge, the expression and function of miR-223 in …

The role of miRNA-223 in cancer: Function, diagnosis and therapy

Y Gao, L Lin, T Li, J Yang, Y Wei - Gene, 2017 - Elsevier
MicroRNAs (miRNAs) constitute a large family of small, non-coding RNAs with the capacity
to regulate gene expression post-transcriptionally. miRNAs appear to hold promise of …

miR-134 increases the antitumor effects of cytarabine by targeting Mnks in acute myeloid leukemia cells

K Chen, Y Chen, Z Chen, Y Shi, Z He… - OncoTargets and …, 2018 - Taylor & Francis
The relapse and resistance to cytarabine (Ara-C) therapy is still a dominating obstacle to the
successful clinical treatment of acute myeloid leukemia (AML). Recent studies have shown …

Low serum miR‐223 expression predicts poor outcome in patients with acute myeloid leukemia

G Yu, Z Yin, H He, Z Zheng, Y Chai… - Journal of Clinical …, 2020 - Wiley Online Library
Background Identification of biomarkers for acute myeloid leukemia (AML) is important for
treating this malignancy. Recent studies have reported that microRNAs (miRNAs) are stably …

MicroRNA‐223 reversibly regulates erythroid and megakaryocytic differentiation of K562 cells

JY Yuan, F Wang, J Yu, GH Yang… - Journal of cellular …, 2009 - Wiley Online Library
MicroRNAs (miRNAs) are thought to modulate a variety of cellular events. Several studies
have revealed the functions of miR‐223 in granulopoiesis. Here we analysed miR‐223 …

microRNA‑125b promotes leukemia cell resistance to daunorubicin by inhibiting apoptosis

L Zhou, H Bai, C Wang, D Wei… - Molecular Medicine …, 2014 - spandidos-publications.com
Abstract microRNA‑125b (miR‑125b) is overexpressed in several types of cancer and
contributes to tumor resistance to chemotherapy. The present study investigated the effect of …

MiR-199a-3p overexpression suppressed cell proliferation and sensitized chronic myeloid leukaemia cells to Imatinib by inhibiting mTOR signalling

X Liu, MM Cui, HZ Zhu, PY Fu, GC Wang… - Acta Haematologica, 2022 - karger.com
Introduction: Chronic myeloid leukaemia (CML) is a myeloproliferative neoplasm
characterized by constitutive activity of the tyrosine kinase BCR-ABL1. Drug resistance …