Helminthiasis is one of the gravest problems worldwide. There is a growing concern on less
available anthelmintics and the emergence of resistance creating a major threat to human …

Background The lack of new anthelmintic agents is of growing concern because it affects
human health and our food supply, as both livestock and plants are affected. Two principal …

The therapeutic arsenal for the control of helminth infections contains only a few chemical
classes. The development and spread of resistance has eroded the utility of most currently …

Parasitic nematodes infect hundreds of millions of people and farmed livestock. Further,
plant parasitic nematodes result in major crop damage. The pipeline of therapeutic …

In the present study, we established a practical and cost-effective high throughput screening
assay, which relies on the measurement of the motility of Caenorhabditis elegans by infrared …

Recent advances in handling and readout have facilitated high-throughput screens with
Caenorhabditis elegans. A new study demonstrates that C. elegans is a useful tool in high …

For more than four decades, the free-living nematode Caenorhabditis elegans has been
extensively used in anthelmintic research. Classic genetic screens and heterologous …

The nematode worm Caenorhabditis elegans is a genetic model organism linked to an
impressive portfolio of fundamental discoveries in biology. This free-living nematode, which …

Highlights•The model host C. elegans is becoming more popular in infectious disease
research.•It is broadly used as an in vivo screening model for new antimicrobial agents.•It …

Drug discovery and drug target identification are two intimately linked facets of intervention
strategies aimed at effectively combating pathological conditions in humans. Simple model …