Objective To provide updated guidance on pre-conception folic acid and multivitamin
supplementation for primary and secondary (recurrence) prevention of neural tube defects …

Objective To provide updated information on the pre-and post-conception use of oral folic
acid with or without a multivitamin/micronutrient supplement for the prevention of neural tube …

More evidence is available for maternal intake, absorption, distribution, tissue specific
concentrations, and pregnancy outcomes with folic acid (fortification/supplementation) …

Large randomized trials have demonstrated the critical role of folic acid supplementation in
the prevention of neural tube defects. Since 1992, a number of national and international …

Importance Neural tube defects are among the most common major congenital anomalies in
the United States and may lead to a range of disabilities or death. Daily folic acid …

Objective To provide information regarding the use of folic acid in combination with a
multivitamin supplement for the prevention of neural tube defects and other congenital …

Objective To provide information regarding the use of folic acid for the prevention of neural
tube defects (NTDs) and other congenital anomalies, in order that physicians, midwives …

Importance Neural tube defects are among the most common congenital malformations in
the US, with an estimated 3000 pregnancies affected each year. Many of these neural tube …

Folate is a water-soluble B vitamin that must be obtained in the diet or through
supplementation. For> 50 yr, it has been known that folate plays an integral role in …

Background: Randomized controlled trials have demonstrated that periconceptional folic
acid supplementation has a dramatic effect in reducing neural tube defects, one of the most …