Retinal vascular endothelial cell dysfunction and neuroretinal degeneration in diabetic patients

M Mrugacz, A Bryl, K Zorena - Journal of clinical medicine, 2021 - mdpi.com
Diabetes mellitus (DM) has become a vital societal problem as epidemiological studies
demonstrate the increasing incidence of type 1 and type 2 diabetes. Lesions observed in the …

Relationships between neurodegeneration and vascular damage in diabetic retinopathy

MG Rossino, M Dal Monte, G Casini - Frontiers in neuroscience, 2019 - frontiersin.org
Diabetic retinopathy (DR) is a common complication of diabetes and constitutes a major
cause of vision impairment and blindness in the world. DR has long been described …

[HTML][HTML] Role of oxidative stress, inflammation, hypoxia and angiogenesis in the development of diabetic retinopathy

AS Al-Kharashi - Saudi journal of ophthalmology, 2018 - Elsevier
Diabetic retinopathy (DR) is a retinal disease which is one of the most severe complications
occuring due to diabetes mellitus and is a major cause of blindness. Patients who have …

Neuro-optic cell apoptosis and microangiopathy in KKAY mouse retina

X Ning, Q Baoyu, L Yuzhen… - International …, 2004 - spandidos-publications.com
Diabetic retinopathy is one of the common complications of diabetes and is the leading
cause for patients' visual dysfunction and sight loss. However, the mechanism of diabetic …

Retinopathy in type 2 diabetes mellitus is associated with increased intima‐media thickness and endothelial dysfunction

MT Malecki, G Osmenda… - European journal of …, 2008 - Wiley Online Library
Background Microangioathy and macroangiopathy in type 2 diabetes mellitus (T2DM)
frequently coexist. Both types of vascular complications share traditional risk factors. It is not …

[HTML][HTML] The cells involved in the pathological process of diabetic retinopathy

S Yang, J Zhang, L Chen - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetic retinopathy (DR) is an expanding global health problem, the exact mechanism of
which has not yet been clarified clearly, new insights into retinal physiology indicate that …

Diabetes induces changes in neuroretina before retinal vessels: a spectral-domain optical coherence tomography study

EB Rodrigues, MG Urias, FM Penha, E Badaró… - International journal of …, 2015 - Springer
Purpose To investigate retinal changes prior to vascular signs in patients with type 2
diabetes without diabetic retinopathy or with mild non proliferative diabetic retinopathy …

Arteriolar involvement in the microvascular lesions of diabetic retinopathy: implications for pathogenesis

TA Gardiner, DB Archer, TM Curtis, AW Stitt - Microcirculation, 2007 - Taylor & Francis
Diabetic retinopathy (DR) is the most widespread complication of diabetes mellitus and a
major cause of blindness in the working population of developed countries. The …

Diabetic retinopathy: loss of neuroretinal adaptation to the diabetic metabolic environment

SF Abcouwer, TW Gardner - Annals of the New York Academy …, 2014 - Wiley Online Library
Diabetic retinopathy (DR) impairs vision of patients with type 1 and type 2 diabetes,
associated with vascular dysfunction and occlusion, retinal edema, hemorrhage, and …

Inflammation in diabetic retinopathy: possible roles in pathogenesis and potential implications for therapy

L Tang, GT Xu, JF Zhang - Neural regeneration research, 2023 - journals.lww.com
Diabetic retinopathy, characterized as a microangiopathy and neurodegenerative disease,
is the leading cause of visual impairment in diabetic patients. Many clinical features …