Infection of PRRSV inhibits CSFV C-strain replication by inducing macrophages polarization to M1

T Tuo, D Chen, L Wang, Y Zhang, L Zhou, X Ge… - Veterinary …, 2024 - Elsevier
It is a common sense that porcine reproductive and respiratory syndrome virus (PRRSV)
infection could cause immune failure of classical swine fever (CSF) vaccine, and porcine …

TNF-α induced by porcine reproductive and respiratory syndrome virus inhibits the replication of classical swine fever virus C-strain

D Chen, X Liu, S Xu, D Chen, L Zhou, X Ge, J Han… - Veterinary …, 2019 - Elsevier
Porcine productive and respiratory syndrome virus (PRRSV) and classical swine fever virus
(CSFV) both are major pathogens of swine that pose a great threat to the Chinese pig …

Porcine alveolar macrophage polarization is involved in inhibition of porcine reproductive and respiratory syndrome virus (PRRSV) replication

L Wang, S Hu, Q Liu, Y Li, L Xu, Z Zhang… - Journal of Veterinary …, 2017 - jstage.jst.go.jp
Macrophage polarization is a process by which macrophages acquire a distinct phenotypic
and functional profile in response to microenvironmental signals. The classically and …

The gene expression profile of porcine alveolar macrophages infected with a highly pathogenic porcine reproductive and respiratory syndrome virus indicates …

Y Xiao, TQ An, ZJ Tian, TC Wei, YF Jiang, JM Peng… - Archives of …, 2015 - Springer
Since the highly pathogenic porcine reproductive and respiratory syndrome virus (HP-
PRRSV) variant emerged in 2006, it has caused death in more than 20 million pigs in China …

Infection of porcine reproductive and respiratory syndrome virus suppresses the antibody response to classical swine fever virus vaccination

H Li, H Yang - Veterinary microbiology, 2003 - Elsevier
The effects of porcine reproductive and respiratory syndrome virus (PRRSV) infection on the
antibody response to vaccination with classical swine fever (CSF) vaccine in piglets were …

Cytokine production in immortalized porcine alveolar macrophages infected with porcine reproductive and respiratory syndrome virus

YJ Lee, C Lee - Veterinary immunology and immunopathology, 2012 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) is one of the most
economically significant viral pathogens for pig production worldwide. PRRSV primarily …

Porcine reproductive and respiratory syndrome virus infection upregulates negative immune regulators and T-cell exhaustion markers

J Chaudhari, CS Liew, JJM Riethoven… - Journal of …, 2021 - Am Soc Microbiol
Porcine alveolar macrophage (PAM) is one of the primary cellular targets for porcine
reproductive and respiratory syndrome virus (PRRSV), but less than 2% of PAMs are …

[HTML][HTML] Functional impairment of PRRSV-specific peripheral CD3+ CD8high cells

S Costers, DJ Lefebvre, B Goddeeris… - Veterinary …, 2009 - ncbi.nlm.nih.gov
The replication of porcine reproductive and respiratory syndrome virus (PRRSV) in lungs
and lymphoid tissues of PRRSV-infected pigs is already strongly reduced before the …

Recombinant antigen of type 2 porcine reproductive and respiratory syndrome virus (PRRSV-2) promotes M1 repolarization of porcine alveolar macrophages and Th1 …

R Wahyuningtyas, YS Lai, ML Wu, HW Chen… - Vaccines, 2021 - mdpi.com
The polarization status of porcine alveolar macrophages (PAMs) determines the infectivity of
porcine reproductive and respiratory syndrome virus (PRRSV). PRRSV infection skews …

Generation of a porcine alveolar macrophage cell line for the growth of porcine reproductive and respiratory syndrome virus

YJ Lee, CK Park, E Nam, SH Kim, OS Lee… - Journal of virological …, 2010 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) has a marked tropism for
cells of the monocyte–macrophage lineage and accordingly, replicates in fully differentiated …