Phytochemicals are potential cancer chemopreventive agents, based partly on cellular
research establishing that phytochemicals inhibit the proliferation of cancer cells. To …

Several epidemiological observations have shown an inverse relation between
consumption of plant-based foods, rich in phytochemicals, and incidence of cancer …

Lesions to DNA trigger the DNA-damage response (DDR), a complex, multi-branched cell-
intrinsic process targeted to DNA repair, or elimination of the damaged cells by apoptosis …

The process of cancer development (carcinogenesis leading to advanced metastasized
cancers) in humans generally takes many years through initiation, promotion and …

Many dietary phytochemicals exhibit health‐beneficial effects including prevention of
diseases such as cancer, as well as neurological, cardiovascular, inflammatory, and …

▪ Abstract Cells in multicellular organisms are exposed to both endogenous oxidative
stresses generated metabolically and to oxidative stresses that originate from neighboring …

Contingent upon concentration, reactive oxygen species (ROS) influence cancer evolution
in apparently contradictory ways, either initiating/stimulating tumorigenesis and supporting …

Oxidative stress imposed by reactive oxygen species (ROS) plays a crucial role in the
pathophysiology associated with neoplasia, atherosclerosis, and neurodegenerative …

Cancer chemopreventive agents block the transformation of normal cells and/or suppress
the promotion of premalignant cells to malignant cells. Certain agents may achieve these …

Oxidative stress is implicated in the etiology of cancer, hence compounds that alleviate
oxidative stress by inducing enzymes that defend against free radical damage might be …