Legume-derived bioactive peptides in type 2 diabetes: opportunities and challenges

K Hu, H Huang, H Li, Y Wei, C Yao - Nutrients, 2023 - mdpi.com
Diabetes mellitus is a complex disorder characterized by insufficient insulin production or
insulin resistance, which results in a lifelong dependence on glucose-lowering drugs for …

Proteins and peptides from vegetable food sources as therapeutic adjuvants for the type 2 diabetes mellitus

I Chan-Zapata, C Sandoval-Castro… - Critical Reviews in …, 2022 - Taylor & Francis
Proteins and peptides are fundamental components of the cereals, pseudocereals, and
legumes, giving them numerous health-beneficial properties. Previous studies have …

In vitro assessment methods for antidiabetic peptides from legumes: A review

A Rahmi, J Arcot - Foods, 2023 - mdpi.com
Almost 65% of the human protein supply in the world originates from plants, with legumes
being one of the highest contributors, comprising between 20 and 40% of the protein supply …

Bioactive peptides as potential nutraceuticals for diabetes therapy: a comprehensive review

P Antony, R Vijayan - International journal of molecular sciences, 2021 - mdpi.com
Diabetes mellitus is a major public health concern associated with high mortality and
reduced life expectancy. The alarming rise in the prevalence of diabetes is linked to several …

Anti-diabetic effects of bioactive peptides: recent advances and clinical implications

C Acquah, CKO Dzuvor, S Tosh… - Critical Reviews in Food …, 2022 - Taylor & Francis
Diabetes mellitus, particularly type 2 diabetes, is a major global health issue, the prevalence
of which seems to be on the rise worldwide. Interventions such as healthy diet, physical …

Bioactive proteins and phytochemicals from legumes: Mechanisms of action preventing obesity and type-2 diabetes

CA Moreno-Valdespino, D Luna-Vital… - Food Research …, 2020 - Elsevier
The Fabaceae family of plants include a variety of seeds with multiple shapes, sizes, and
colors; with a great diversity of bioactive compounds found in legume seeds. Legumes are …

Insulin-like proteins in plant sources: a systematic review

IS Costa, AF Medeiros, G Piuvezam… - Diabetes, Metabolic …, 2020 - Taylor & Francis
Type 2 diabetes mellitus (T2DM) is characterized by hyperglycemia. Proteins in plant
sources that enable the maintenance of the glycemic profile may be of interest in the context …

Antidiabetic food-derived peptides for functional feeding: Production, functionality and in vivo evidences

F Rivero-Pino, FJ Espejo-Carpio, EM Guadix - Foods, 2020 - mdpi.com
Bioactive peptides released from the enzymatic hydrolysis of food proteins are currently a
trending topic in the scientific community. Their potential as antidiabetic agents, by …

Characteristics of food protein-derived antidiabetic bioactive peptides: A literature update

NTP Nong, JL Hsu - International Journal of Molecular Sciences, 2021 - mdpi.com
Diabetes, a glucose metabolic disorder, is considered one of the biggest challenges
associated with a complex complication of health crises in the modern lifestyle. Inhibition or …

Legume-derived bioactive peptides: Role in cardiovascular disease prevention and control

DF Hernandez, L Mojica, EG de Mejia - Current Opinion in Food Science, 2024 - Elsevier
Highlights•Legume-derived peptides can reduce cardiovascular diseases
progression.•Bioactive peptides activate novel pathways for cardiovascular diseases …